4-Methoxyphenylmagnesium bromide solution
4-Methoxyphenylmagnesium bromide solution (CAS: 13139-86-1, CH3OC6H4MgBr, MW: 211.34) is an organometallic compound, specifically a Grignard reagent. It is supplied as a 0.5 M solution in Tetrahydrofuran (THF). This reactive intermediate is widely employed in organic synthesis for carbon-carbon bond formation, particularly in the introduction of the 4-methoxyphenyl group into various molecular structures.

Organic Synthesis Intermediate
Serves as a key reagent in the synthesis of complex organic molecules by facilitating the formation of new carbon-carbon bonds through nucleophilic addition.
Introduction of Aryl Groups
Used to introduce the 4-methoxyphenyl moiety into target molecules, a common structural feature in pharmaceuticals and fine chemicals.
Grignard Reactions
Participates in a wide range of Grignard reactions, reacting with electrophiles such as aldehydes, ketones, esters, and nitriles.
| Molecular weight | 211.34 |
|---|---|
| Linear formula | CH3OC6H4MgBr |
| Boiling point | 65-67 °C |
| Density | 0.955 g/mL at 25 °C |
| Concentration | 0.5 M in THF |




Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -20 °C / -4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxyphenylmagnesium bromide solution used for?
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This Grignard reagent is primarily used as an intermediate in organic synthesis for forming carbon-carbon bonds and introducing the 4-methoxyphenyl group into various compounds.
What are the CAS number and formula for this compound?
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The CAS number is 13139-86-1 and the linear formula is CH3OC6H4MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 0.5 M solution in THF. We do not represent it as USP, BP, or EP grade. Purity information is available on the Certificate of Analysis.
How should 4-Methoxyphenylmagnesium bromide solution be handled?
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This solution is highly flammable (Flash Point: -20 °C) and corrosive. It reacts violently with water and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources, and avoid contact with water. Refer to the Safety Data Sheet for detailed handling instructions.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Methoxyphenylmagnesium bromide solution.
How can I request a sample or quote for 4-Methoxyphenylmagnesium bromide solution?
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Please contact our sales team directly via phone or email to request a sample or a formal quotation.
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