4-Methoxyphenylacetyl chloride
4-Methoxyphenylacetyl chloride (CAS: 4693-91-8) is an organic compound with the linear formula CH₃OC₆H₄CH₂COCl and a molecular weight of 184.62 g/mol. This acid halide serves as a valuable intermediate in organic synthesis, particularly for introducing the 4-methoxyphenylacetyl moiety into various molecules. Its reactive nature makes it suitable for esterification, amidation, and Friedel-Crafts acylation reactions in the development of pharmaceuticals and other fine chemicals.
Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of complex organic molecules. Its acyl chloride functionality readily reacts with nucleophiles to form esters and amides, facilitating the construction of diverse chemical structures.
Pharmaceutical Research
Employed in the development pathway for potential pharmaceutical agents. The 4-methoxyphenylacetyl group can be incorporated into drug candidates to modulate their biological activity and pharmacokinetic properties.
Fine Chemical Manufacturing
Acts as a versatile reagent in the production of fine chemicals. Its application extends to the creation of speciality chemicals and materials where the specific structural unit is required.
| Molecular weight | 184.62 |
|---|---|
| Linear formula | CH3OC6H4CH2COCl |
| Assay | 98% |
| Boiling point | 143 °C/10 mmHg(lit.) |
| Density | 1.208 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.54(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxyphenylacetyl chloride used for?
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4-Methoxyphenylacetyl chloride is primarily used as an intermediate in organic synthesis, particularly for introducing the 4-methoxyphenylacetyl group in the development of pharmaceuticals and fine chemicals.
What is the CAS number and formula for 4-Methoxyphenylacetyl chloride?
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The CAS number is 4693-91-8 and the linear formula is CH₃OC₆H₄CH₂COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxyphenylacetyl chloride with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 4-Methoxyphenylacetyl chloride be handled?
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4-Methoxyphenylacetyl chloride is a corrosive substance that reacts violently with water. Handle with extreme caution using appropriate personal protective equipment, including a full-face respirator, gloves, and goggles, in a well-ventilated area. Avoid contact with water and moisture.
How is 4-Methoxyphenylacetyl chloride packed, shipped, and exported?
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Our products are carefully packed according to international shipping regulations, ensuring safe transit. We have extensive experience exporting chemicals globally.
How can I request a sample or quote for 4-Methoxyphenylacetyl chloride?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your specific requirements and delivery details.
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