4-Methoxyphenyl chloroformate
4-Methoxyphenyl chloroformate (CAS: 7693-41-6) is an organic acid halide with a molecular weight of 186.59 g/mol. This compound serves as a valuable intermediate and building block in organic synthesis. Its reactive nature makes it suitable for various chemical transformations, particularly in the preparation of carbonates and carbamates, finding utility in research and development settings for creating more complex molecules.

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of various organic compounds. It is employed in the formation of carbonates and carbamates, essential moieties in pharmaceuticals and agrochemicals.
Protecting Group Chemistry
Can be used for the introduction of the 4-methoxyphenylcarbonyl protecting group onto alcohols and amines. This protecting group can be selectively removed under specific conditions.
Reagent in Esterification and Amidation
Facilitates the formation of esters and amides through reactions with carboxylic acids or amines, respectively. This reactivity is fundamental in constructing diverse molecular architectures.
| Molecular weight | 186.59 |
|---|---|
| Linear formula | ClCO2C6H4OCH3 |
| Assay | 98% |
| Boiling point | 49 °C/0.27 mmHg(lit.) |
| Density | 1.255 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5254(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3277 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,C |
| Risk statements (R) | 23/24/25-34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxyphenyl chloroformate used for?
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4-Methoxyphenyl chloroformate is primarily used as an intermediate and building block in organic synthesis, particularly for preparing carbonates and carbamates. It also functions in protecting group chemistry and as a reagent in esterification and amidation reactions.
What is the CAS number and formula for 4-Methoxyphenyl chloroformate?
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The CAS number is 7693-41-6 and the linear formula is ClCO <sub>2</sub>C <sub>6</sub>H <sub>4</sub>OCH <sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxyphenyl chloroformate with an assay of 98%. This is a technical/research grade chemical; TSS does not represent it as USP, BP, or EP.
How should 4-Methoxyphenyl chloroformate be handled safely?
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4-Methoxyphenyl chloroformate is a dangerous substance, indicated by GHS symbols for corrosion and toxicity (Danger). It is toxic if swallowed, in contact with skin, and if inhaled, and causes severe skin burns and eye damage. Appropriate personal protective equipment, including gloves, goggles, and a full-face respirator, must be used. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is 4-Methoxyphenyl chloroformate packed and shipped?
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4-Methoxyphenyl chloroformate is packed and shipped according to relevant regulations, designated as UN 3277, Class 6.1, Packing Group II. TSS ensures compliance with all export and shipping requirements for hazardous materials.
How can I request a sample or quote for 4-Methoxyphenyl chloroformate?
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To request a sample or a quote for 4-Methoxyphenyl chloroformate, please contact the TSS sales department via our website or direct inquiry channels, providing your specific requirements and shipping details.
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