4′-Hydroxy-3′-methoxyacetophenone
4′-Hydroxy-3′-methoxyacetophenone (CAS 498-02-2) is a key organic building block with the linear formula HOC₆H₃(OCH₃)COCH₃ and a molecular weight of 166.17 g/mol. This carbonyl compound, also known as Apocynin, is primarily utilised in chemical synthesis and as a precursor for more complex molecules in research and development. Its properties make it valuable in various organic chemistry applications.
- IUPAC
- Acetovanillone,Apocynin
- Synonyms
- AcetovanilloneApocynin

Organic Synthesis Intermediate
As a substituted acetophenone, 4′-Hydroxy-3′-methoxyacetophenone serves as a versatile intermediate in the synthesis of various organic compounds. Its functional groups allow for diverse chemical transformations, making it a useful building block in multi-step synthetic pathways.
Research and Development
This compound is employed in academic and industrial research laboratories for exploring novel chemical reactions and developing new materials. Its well-defined structure facilitates its use in studies requiring specific molecular architectures.
Precursor for Pharmaceuticals and Agrochemicals
While specific applications are not detailed, compounds with similar structural motifs are often investigated as potential pharmaceutical or agrochemical agents. 4′-Hydroxy-3′-methoxyacetophenone can act as a starting material in the discovery phases for these industries.
| Molecular weight | 166.17 |
|---|---|
| Linear formula | HOC6H3(OCH3)COCH3 |
| Assay | 98% |
| Boiling point | 263-265 °C/17 mmHg(lit.) |
| Melting point | 112-115 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Hydroxy-3′-methoxyacetophenone used for?
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4′-Hydroxy-3′-methoxyacetophenone is primarily used as a versatile intermediate in organic synthesis and in research and development for exploring new chemical pathways and molecules.
What are the CAS number and chemical formula for 4′-Hydroxy-3′-methoxyacetophenone?
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The CAS number is 498-02-2 and the linear chemical formula is HOC₆H₃(OCH₃)COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Hydroxy-3′-methoxyacetophenone with an assay of 98%. TSS does not represent this product as USP, BP, or EP grade.
How should 4′-Hydroxy-3′-methoxyacetophenone be handled safely?
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Handle with care: 4′-Hydroxy-3′-methoxyacetophenone is classified with GHS07 warning, indicating it may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for safe transport and export of 4′-Hydroxy-3′-methoxyacetophenone.
How can I request a sample or quote for 4′-Hydroxy-3′-methoxyacetophenone?
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To request a sample or a quote for 4′-Hydroxy-3′-methoxyacetophenone, please contact our sales team through the TSS website or provide your details via the product inquiry form.
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