4-Hydroxy-1-piperidineethanol
4-Hydroxy-1-piperidineethanol (CAS 224431-84-9), with the empirical formula C7H15NO2 and a molecular weight of 145.20 g/mol, is a heterocyclic building block. This compound serves as a valuable reactant in chemical synthesis, particularly for the development of novel estrogen receptor ligands and agents with antiproliferative effects against breast cancer cells. Its structure facilitates diverse synthetic pathways in pharmaceutical research.
- IUPAC
- 1-(2-Hydroxyethyl)-4-hydroxypiperidine,4-Hydroxy-1-piperidineethanol
- Synonyms
- 1-(2-Hydroxyethyl)-4-hydroxypiperidine
Synthesis of Estrogen Receptor Ligands
4-Hydroxy-1-piperidineethanol is utilised as a key reactant in the synthesis of compounds designed to interact with estrogen receptors. This is crucial in the research and development of targeted therapies.
Development of Antiproliferative Agents
This chemical building block is employed in the creation of novel agents aimed at inhibiting the proliferation of breast cancer cells. Its specific structural features contribute to the efficacy of these therapeutic candidates.
Heterocyclic Compound Synthesis
As a piperidine derivative, 4-Hydroxy-1-piperidineethanol is a versatile intermediate for constructing more complex heterocyclic structures relevant to medicinal chemistry and materials science.
| Molecular weight | 145.20 |
|---|---|
| Empirical formula | C7H15NO2 |
| Assay | 96% |
| Application | Reactant for synthesis of estrogen receptor ligands and breast cancer cell antiproliferative agents1 |
| Melting point | 33-40 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-1-piperidineethanol used for?
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4-Hydroxy-1-piperidineethanol is primarily used as a reactant in the synthesis of estrogen receptor ligands and agents with antiproliferative effects against breast cancer cells. It also serves as a versatile building block in general chemical synthesis.
What is the CAS number and chemical formula for 4-Hydroxy-1-piperidineethanol?
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The CAS number is 224431-84-9 and the empirical formula is C7H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-1-piperidineethanol with an assay of 96%. This product is not supplied as USP, BP, or EP grade.
What are the safety hazards associated with 4-Hydroxy-1-piperidineethanol?
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4-Hydroxy-1-piperidineethanol presents significant hazards, indicated by GHS symbols for corrosion and irritation. It is classified as Danger, with hazard statements H315 (causes skin irritation), H318 (causes serious eye damage), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, is essential during handling.
How is 4-Hydroxy-1-piperidineethanol packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details for 4-Hydroxy-1-piperidineethanol are available upon request and will comply with all relevant international regulations for hazardous materials.
How can I request a sample or quote for 4-Hydroxy-1-piperidineethanol?
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To request a sample or a quotation for 4-Hydroxy-1-piperidineethanol, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
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