4-Hydroxy-1-naphthaldehyde
4-Hydroxy-1-naphthaldehyde (CAS: 7770-45-8), with the molecular formula HOC10H7CHO and a molecular weight of 172.18, is a key organic building block. This compound serves as a valuable intermediate in chemical synthesis. It is particularly noted for its use in the preparation of various naphthol analogues of amino acids, contributing to advancements in organic chemistry research and development. Supplied by Tech Serve Solutions with an assay of 98%.
Synthesis of Naphthylalanine Analogues
4-Hydroxy-1-naphthaldehyde is utilized as a precursor in the synthesis of racemic 1- and 2-naphthol analogues of tyrosine. This includes the preparation of 2-amino-3-(4-hydroxy-1-naphthyl)propanoic acid hydrochloride and 2-amino-3-(6-hydroxy-2-naphthyl)propanoic acid hydrobromide, highlighting its role in complex organic synthesis.
Organic Building Block
As a functionalised naphthalene derivative containing both aldehyde and hydroxyl groups, 4-Hydroxy-1-naphthaldehyde is a versatile building block for constructing more complex organic molecules. Its structure facilitates diverse chemical transformations in research and development.
Carbonyl Compound Intermediate
This compound belongs to the class of carbonyl compounds, specifically aldehydes, and is employed in various chemical synthesis pathways where the aldehyde functionality is required for further reactions, such as condensations or reductions.
| Molecular weight | 172.18 |
|---|---|
| Linear formula | HOC10H7CHO |
| Assay | 98% |
| Application | 4-Hydroxy-1-naphthaldehyde was used in the preparation of racemic 1- and 2-naphthol analogues of tyrosine, 2-amino-3-(4-hydroxy-1-naphthyl)propanoic acid hydrochloride and 2-amino-3-(6-hydroxy-2-naphthyl)propanoic acid hydrobromide1. |
| Melting point | 179-182 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-1-naphthaldehyde used for?
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4-Hydroxy-1-naphthaldehyde is used as an intermediate in chemical synthesis, particularly for preparing naphthylalanine analogues and other complex organic molecules.
What are the CAS number and molecular formula for 4-Hydroxy-1-naphthaldehyde?
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The CAS number is 7770-45-8 and the molecular formula is HOC10H7CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-1-naphthaldehyde with a minimum assay of 98%. This is a technical/research grade product and is not represented as USP, BP, or EP grade.
How should 4-Hydroxy-1-naphthaldehyde be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation. Avoid breathing dust. Causes skin irritation, eye irritation, and may cause respiratory irritation (H315, H319, H335).
How is 4-Hydroxy-1-naphthaldehyde packed and exported?
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4-Hydroxy-1-naphthaldehyde is carefully packed to maintain its integrity during transport and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 4-Hydroxy-1-naphthaldehyde?
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To request a sample or a quote, please contact Tech Serve Solutions via our website or your dedicated sales representative, providing the product name and CAS number (7770-45-8).
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