4-Cyanophenylboronic acid pinacol ester
4-Cyanophenylboronic acid pinacol ester (CAS: 171364-82-2, Formula: C13H16BNO2) is an organoboron compound with a molecular weight of 229.08 g/mol. It functions as a valuable building block in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling. Its structure makes it useful for introducing the 4-cyanophenyl moiety into complex molecules, finding applications in the development of pharmaceuticals, advanced materials, and organic electronic components.
- IUPAC
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
Suzuki-Miyaura Cross-Coupling
This pinacol ester is widely employed as a coupling partner in palladium-catalyzed Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate Synthesis
The 4-cyanophenyl group is present in various biologically active molecules. This boronate ester serves as a key intermediate for the efficient synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
Materials Science
It can be incorporated into polymers or small molecules designed for organic electronics, such as organic light-emitting diodes (OLEDs) or organic photovoltaics (OPVs), due to the electronic properties conferred by the cyanophenyl group.
Agrochemical Research
Used in the synthesis of novel compounds with potential pesticidal or herbicidal activity, contributing to the development of new crop protection agents.
| Molecular weight | 229.08 |
|---|---|
| Empirical formula | C13H16BNO2 |
| Assay | 97% |
| Melting point | 95-99 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Cyanophenylboronic acid pinacol ester used for?
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4-Cyanophenylboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is instrumental in the synthesis of pharmaceuticals, materials for organic electronics, and agrochemicals.
What are the CAS number and molecular formula?
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The CAS number is 171364-82-2, and the molecular formula is C13H16BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Cyanophenylboronic acid pinacol ester with an assay of 97%. This product is supplied for research and development purposes. Tech Serve Solutions does not represent this product as USP, EP, BP, or other pharmacopoeia grades.
How should 4-Cyanophenylboronic acid pinacol ester be handled?
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Handle with care. This compound is classified as an irritant, potentially causing skin (H315), eye (H319), and respiratory tract irritation (H335). Use appropriate personal protective equipment, including a dust mask (type N95 or equivalent), safety eyeshields, and gloves. Ensure adequate ventilation or use in a fume hood.
Is this compound a controlled substance?
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Based on the provided data, there is no indication that 4-Cyanophenylboronic acid pinacol ester (CAS: 171364-82-2) is a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to international shipping regulations to ensure safe and compliant delivery.
How can I request a quote or sample?
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To request a quote or sample of 4-Cyanophenylboronic acid pinacol ester, please contact our sales team through the website or by phone, providing your specific requirements.
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