4-Chloro-8-fluoro-2-methylquinoline
4-Chloro-8-fluoro-2-methylquinoline (CAS: 18615-59-3) is a fluorinated heterocyclic compound with the molecular formula C10H7ClFN and a molecular weight of 195.62 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly within the fields of medicinal chemistry and materials science. Its unique structure, featuring both chlorine and fluorine substituents on a quinoline core, allows for diverse chemical transformations and incorporation into complex molecular architectures.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of more complex organic molecules. The presence of halogen atoms provides reactive sites for various coupling reactions and nucleophilic substitutions.
Medicinal Chemistry Research
Serves as a scaffold for the development of novel pharmaceutical agents. The quinoline core and fluorine substitution are common features in biologically active compounds.
Materials Science
Potential applications in the development of functional materials due to the incorporation of fluorine, which can influence properties such as electronic behaviour and thermal stability.
| Molecular weight | 195.62 |
|---|---|
| Empirical formula | C10H7ClFN |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-8-fluoro-2-methylquinoline used for?
+
4-Chloro-8-fluoro-2-methylquinoline is primarily used as a building block in organic synthesis, with applications in medicinal chemistry research and potentially in materials science.
What is the CAS number and molecular formula for 4-Chloro-8-fluoro-2-methylquinoline?
+
The CAS number is 18615-59-3, and the molecular formula is C10H7ClFN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific assay and purity are available upon request; we do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for 4-Chloro-8-fluoro-2-methylquinoline?
+
This compound is classified as Dangerous (Signal Word: Danger). It is harmful if swallowed (H302) and causes serious eye damage (H318). Appropriate personal protective equipment, including eye protection, should be worn during handling.
How is 4-Chloro-8-fluoro-2-methylquinoline packaged and shipped?
+
Tech Serve Solutions handles the packaging and shipping of chemicals with adherence to all relevant regulations, facilitating global export.
How can I request a sample or quote for 4-Chloro-8-fluoro-2-methylquinoline?
+
To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis