4-Chloro-7-(trifluoromethyl)quinoline
4-Chloro-7-(trifluoromethyl)quinoline (CAS: 346-55-4) is a halogenated heterocyclic compound with the molecular formula C10H5ClF3N and a molecular weight of 231.60 g/mol. It serves as a valuable building block in organic synthesis, particularly for creating more complex molecules within the C8 to C10 carbon range. Its primary utility lies in the synthesis of various chemical intermediates and potentially pharmaceutical compounds, leveraging the reactive chloro and trifluoromethyl quinoline core structure.
Synthesis of Aminobenzoates and Aminonicotinates
This compound has been utilised in the synthetic pathways for preparing (4-substituted phenyl-1-piperazinyl) alkyl 2-aminobenzoates and 2-aminonicotinates, highlighting its role in constructing complex heterocyclic systems.
Chemical Synthesis Intermediate
As a halogenated heterocycle, 4-Chloro-7-(trifluoromethyl)quinoline is an important intermediate in various chemical synthesis processes. Its structure allows for diverse functional group transformations.
Building Block for Heterocycles
It functions as a key building block in the synthesis of diverse heterocyclic compounds, contributing to the development of novel molecules with potential applications in material science and medicinal chemistry.
| Molecular weight | 231.60 |
|---|---|
| Empirical formula | C10H5ClF3N |
| Assay | 98% |
| Solubility | chloroform: soluble25 mg/mL, clear, colorless |
| Application | 4-Chloro-7-(trifluoromethyl)quinolone was used in the synthesis of (4-substituted phenyl-1-piperazinyl) alkyl 2-aminobenzoates and 2-aminonicotinates1. |
| Melting point | 69-71 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-7-(trifluoromethyl)quinoline used for?
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4-Chloro-7-(trifluoromethyl)quinoline is primarily used as a building block in organic synthesis, notably in the preparation of compounds like (4-substituted phenyl-1-piperazinyl) alkyl 2-aminobenzoates and 2-aminonicotinates.
What are the CAS number and chemical formula?
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The CAS number for 4-Chloro-7-(trifluoromethyl)quinoline is 346-55-4, and its chemical formula is C10H5ClF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-7-(trifluoromethyl)quinoline with an assay of 98%. We do not represent this product as meeting any specific pharmacopoeia standards such as USP, BP, or EP.
How should 4-Chloro-7-(trifluoromethyl)quinoline be handled?
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This compound is a Warning irritant, causing skin (H315), eye (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves, should be used. Ensure adequate ventilation.
How is this chemical packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and handles the export of 4-Chloro-7-(trifluoromethyl)quinoline in compliance with all relevant regulations.
How can I request a sample or quote?
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To request a sample or obtain a quotation for 4-Chloro-7-(trifluoromethyl)quinoline, please contact our sales department through the TSS website or by telephone.
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