4′-Chloro-5-fluoro-2-hydroxybenzophenone
4′-Chloro-5-fluoro-2-hydroxybenzophenone (CAS 62433-26-5), with the molecular formula ClC6H4COC6H3(F)OH and a molecular weight of 250.65, is a versatile organic intermediate. This halogenated benzophenone derivative serves as a valuable building block in complex chemical syntheses, particularly within the pharmaceutical and fine chemical industries. Its specific structural features, including the chloro, fluoro, and hydroxyl groups, enable targeted reactions for developing advanced materials and active pharmaceutical ingredients.

Synthesis of Pharmaceutical Intermediates
This compound acts as a key intermediate in the synthesis of various pharmaceutical agents. Its reactive sites allow for functional group transformations critical in constructing complex drug molecules.
Organic Synthesis Building Block
As a functionalised benzophenone, it is employed in diverse organic synthesis pathways. It facilitates the introduction of specific chloro-fluoro-hydroxyphenyl moieties into larger molecular structures.
Material Science Research
The unique combination of halogen and hydroxyl substituents makes it a candidate for research in developing novel functional materials with specific electronic or optical properties.
| Molecular weight | 250.65 |
|---|---|
| Linear formula | ClC6H4COC6H3(F)OH |
| Assay | 96% |
| Melting point | 65-69 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Chloro-5-fluoro-2-hydroxybenzophenone used for?
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4′-Chloro-5-fluoro-2-hydroxybenzophenone is primarily used as a building block in organic synthesis, particularly for creating pharmaceutical intermediates and potentially in material science research.
What are the CAS number and chemical formula for this compound?
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The CAS number is 62433-26-5 and the chemical formula is ClC6H4COC6H3(F)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a minimum purity of 96% (Assay). TSS does not represent this product as USP, EP, BP, or any other pharmacopoeia grade unless explicitly stated.
How should 4′-Chloro-5-fluoro-2-hydroxybenzophenone be handled?
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This compound is classified as an irritant. Handle with appropriate personal protective equipment including eyeshields, gloves, and a dust mask (type N95 or equivalent). Ensure adequate ventilation to avoid inhalation of dust, and avoid contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed handling procedures.
Is 4′-Chloro-5-fluoro-2-hydroxybenzophenone a controlled substance?
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Based on the provided data, there is no indication that 4′-Chloro-5-fluoro-2-hydroxybenzophenone is a controlled substance.
How is 4′-Chloro-5-fluoro-2-hydroxybenzophenone packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports chemicals globally, adhering to all relevant international regulations and safety standards for hazardous materials.
How can I request a sample or quote for 4′-Chloro-5-fluoro-2-hydroxybenzophenone?
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To request a sample or a quote, please contact our sales team through the provided contact details on the Tech Serve Solutions website.
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