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4′-Chloro-3′-nitroacetophenone

CAS 5465-65-6ClC6H3(NO2)COCH3Chemical Synthesis

4′-Chloro-3′-nitroacetophenone (CAS: 5465-65-6) is an organic compound with the linear formula ClC₆H₃(NO₂)COCH₃ and a molecular weight of 199.59 g/mol. This chemical serves as a crucial building block in organic synthesis. It is primarily utilized as a starting reagent in the preparation of more complex molecules, including quinoxaline derivatives, contributing to advancements in chemical research and development.

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4′-Chloro-3′-nitroacetophenone (ClC6H3(NO2)COCH3) — chemical structure, CAS 5465-65-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC7 to C8Carbonyl CompoundsChemical SynthesisKetones
01 /Applications

Synthesis of Quinoxaline Derivatives

4′-Chloro-3′-nitroacetophenone is employed as a key starting material in the synthesis of 6- and 7-acetyl-3-methyl-2-quinoxalinecarboxamide 1,4-dioxides. This application highlights its utility in constructing complex heterocyclic systems.

Organic Synthesis Building Block

As a versatile building block, this compound is valuable for introducing specific functional groups into organic molecules. Its structure allows for further chemical modifications, making it useful in multi-step synthetic routes.

Chemical Research and Development

Researchers utilize 4′-Chloro-3′-nitroacetophenone in laboratory settings for exploring new synthetic pathways and developing novel chemical entities. Its availability supports innovation in various chemical disciplines.

02 /Properties
Molecular weight199.59
Linear formulaClC6H3(NO2)COCH3
Assay99%
Application4′-Chloro-3′-nitroacetophenone was used to prepare starting reagent for the synthesis of 6- and 7-acetyl-3-methyl-2-quinoxalinecarboxamide1,4-dioxides1.
Melting point99-101 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
5465-65-6
MDL number
MFCD00007083
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4′-Chloro-3′-nitroacetophenone used for?

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4′-Chloro-3′-nitroacetophenone is primarily used as a building block in organic synthesis. It serves as a starting reagent for preparing compounds like quinoxaline derivatives, contributing to chemical research and development.

What are the CAS number and chemical formula for 4′-Chloro-3′-nitroacetophenone?

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The CAS number for 4′-Chloro-3′-nitroacetophenone is 5465-65-6, and its linear formula is ClC₆H₃(NO₂)COCH₃.

What grade and purity does Tech Serve Solutions supply for 4′-Chloro-3′-nitroacetophenone?

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Tech Serve Solutions supplies 4′-Chloro-3′-nitroacetophenone with an assay of 99%. We do not represent this product as meeting USP, BP, EP, or any pharmacopoeia standards.

What are the main safety hazards associated with 4′-Chloro-3′-nitroacetophenone?

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4′-Chloro-3′-nitroacetophenone is classified with a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used.

How is 4′-Chloro-3′-nitroacetophenone packed, shipped, and exported?

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Tech Serve Solutions, as a specialist global supplier and exporter, handles the packing, shipping, and international export of 4′-Chloro-3′-nitroacetophenone in compliance with all relevant regulations.

How can I request a sample or quote for 4′-Chloro-3′-nitroacetophenone?

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To request a sample or a quote for 4′-Chloro-3′-nitroacetophenone, please contact our sales team through the website or via direct inquiry.

Need 4′-Chloro-3′-nitroacetophenone in a specific grade or volume?