4-Chloro-2-nitrobenzyl chloride
4-Chloro-2-nitrobenzyl chloride (CAS: 938-71-6), with the molecular formula ClC6H3(NO2)CH2Cl and a molecular weight of 206.03 g/mol, is a specialised organic intermediate. It is primarily employed as a chemical building block in organic synthesis. The compound serves as a precursor in the preparation of more complex molecules, including pharmaceutical intermediates and research compounds. Its defined structure makes it valuable for targeted chemical reactions and research applications.
- IUPAC
- α,4-Dichloro-2-nitrotoluene
- Synonyms
- α,4-Dichloro-2-nitrotoluene

Intermediate in Organic Synthesis
4-Chloro-2-nitrobenzyl chloride acts as a key intermediate for the synthesis of various organic compounds. Its reactive benzyl chloride and nitro functionalities allow for diverse chemical transformations.
Synthesis of Pharmaceutical Intermediates
This compound has been utilised in the preparation of specific pharmaceutical intermediates, such as 3-iodothyronamine. Its structural features are instrumental in building complex drug scaffolds.
Research and Development
As a well-defined organic building block, 4-Chloro-2-nitrobenzyl chloride is valuable for chemical research and development activities, enabling the exploration of novel synthetic pathways and materials.
| Molecular weight | 206.03 |
|---|---|
| Linear formula | ClC6H3(NO2)CH2Cl |
| Assay | 98% |
| Application | 4-Chloro-2-nitrobenzyl chloride has been used in the synthesis of 3-iodothyronamine1. |
| Melting point | 38-44 °C(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2-nitrobenzyl chloride used for?
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4-Chloro-2-nitrobenzyl chloride is used as a chemical building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates and in research and development activities.
What is the CAS number and chemical formula for 4-Chloro-2-nitrobenzyl chloride?
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The CAS number is 938-71-6 and the chemical formula is ClC6H3(NO2)CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-2-nitrobenzyl chloride with an assay of 98%. This product is intended for laboratory and industrial use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 4-Chloro-2-nitrobenzyl chloride be handled safely?
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This compound is classified as corrosive and may cause respiratory irritation. It requires careful handling with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 type filters/cartridges), in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive safety information.
Does TSS export 4-Chloro-2-nitrobenzyl chloride?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-2-nitrobenzyl chloride.
How can I request a quote or sample for 4-Chloro-2-nitrobenzyl chloride?
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To request a quote or sample, please contact our sales department via the website or provide your details through the enquiry form, specifying the product and quantity required.
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