4-Chloro-2-nitrobenzenesulfonyl chloride
4-Chloro-2-nitrobenzenesulfonyl chloride (CAS: 4533-96-4; Formula: C6H3Cl2NO4S) is a reactive organic compound with a molecular weight of 256.06 g/mol. This chemical serves as a valuable building block and intermediate in organic synthesis, particularly in the functionalisation of molecules through its sulfonyl chloride group. It is a key reagent for introducing the 4-chloro-2-nitrobenzenesulfonyl moiety into various organic structures, finding utility in the development of pharmaceuticals and other fine chemicals.

Organic Synthesis Intermediate
Utilised as a building block for the synthesis of more complex organic molecules. Its reactive sulfonyl chloride group allows for facile derivatisation.
Pharmaceutical Research
Employed in the preparation of novel drug candidates and intermediates. The 4-chloro-2-nitrobenzenesulfonyl moiety can be incorporated to modify pharmacological properties.
Fine Chemical Production
A reagent for the manufacturing of specialised fine chemicals where the specific structural features of 4-chloro-2-nitrobenzenesulfonyl chloride are required.
| Molecular weight | 256.06 |
|---|---|
| Empirical formula | C6H3Cl2NO4S |
| Assay | 97% |
| Melting point | 75-79 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2-nitrobenzenesulfonyl chloride used for?
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4-Chloro-2-nitrobenzenesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and other fine chemicals.
What is the CAS number and formula for 4-Chloro-2-nitrobenzenesulfonyl chloride?
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The CAS number is 4533-96-4, and the molecular formula is C6H3Cl2NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-2-nitrobenzenesulfonyl chloride with an assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 4-Chloro-2-nitrobenzenesulfonyl chloride be handled?
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4-Chloro-2-nitrobenzenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment (P280) and follow emergency procedures (P305 + P351 + P338, P310).
How is 4-Chloro-2-nitrobenzenesulfonyl chloride packed and exported?
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This compound is shipped as UN 3261, Class 8, Packing Group II. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for 4-Chloro-2-nitrobenzenesulfonyl chloride?
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Please contact our sales team or use the online inquiry form to request a sample or a quotation for 4-Chloro-2-nitrobenzenesulfonyl chloride.
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