4-Bromobenzenesulfonyl chloride
4-Bromobenzenesulfonyl chloride (CAS: 98-58-8, Formula: BrC6H4SO2Cl) is a chemical compound with a molecular weight of 255.52. It functions as a key building block in organic synthesis. Primarily utilised as an activating agent in the preparation of nucleotide analogues and in the synthesis of complex organic molecules such as 4-(N-allylsulfamoyl)phenylboronic acid. Its reactivity makes it valuable in the field of chemical research and development.

Nucleotide Synthesis
Serves as an activating agent in the solution-phase synthesis of oligodeoxyribo- and oligoribo- nucleotides, facilitating the formation of phosphodiester bonds.
Organic Synthesis Reagent
Employed in the synthesis of various organic intermediates, including the preparation of 4-(N-allylsulfamoyl)phenylboronic acid.
Building Block for Complex Molecules
Its structure makes it a useful starting material or intermediate for constructing more complex chemical architectures in research settings.
| Molecular weight | 255.52 |
|---|---|
| Linear formula | BrC6H4SO2Cl |
| Assay | 98% |
| Boiling point | 153 °C/15 mmHg(lit.) |
| Application | 4-Bromobenzenesulfonyl chloride was used as activating agent in the synthesis of oligodeoxyribo- and oligoribo- nucleotides in solution1. It was used in the synthesis of 4-(N-allylsulfamoyl)phenylboronic acid2. |
| Melting point | 73-75 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromobenzenesulfonyl chloride used for?
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4-Bromobenzenesulfonyl chloride is used as an activating agent in the synthesis of nucleotide analogues and as a building block in organic synthesis, for example, in the preparation of 4-(N-allylsulfamoyl)phenylboronic acid.
What is the CAS number and formula for 4-Bromobenzenesulfonyl chloride?
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The CAS number is 98-58-8 and the chemical formula is BrC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromobenzenesulfonyl chloride with a minimum assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
How should 4-Bromobenzenesulfonyl chloride be handled safely?
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4-Bromobenzenesulfonyl chloride is classified as Danger, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Is 4-Bromobenzenesulfonyl chloride a controlled substance?
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The provided data does not indicate that 4-Bromobenzenesulfonyl chloride is a controlled substance.
How is 4-Bromobenzenesulfonyl chloride packed and shipped?
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4-Bromobenzenesulfonyl chloride is shipped as UN 3261, Class 8, Packing Group II. Specific packaging details are available upon request.
How can I request a sample or quote for 4-Bromobenzenesulfonyl chloride?
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To request a sample or a quotation for 4-Bromobenzenesulfonyl chloride, please contact the Tech Serve Solutions sales team through our website or by phone.
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