4-Bromobenzoic hydrazide
4-Bromobenzoic hydrazide (CAS 5933-32-4) is a key organic building block with the linear formula BrC<sub>6</sub>H<sub>4</sub>CONHNH<sub>2</sub> and a molecular weight of 215.05 g/mol. This compound serves as a versatile intermediate in chemical synthesis, particularly for the preparation of various heterocyclic compounds and complex organic molecules. Its primary applications lie in research and development laboratories focused on organic chemistry and medicinal chemistry.
Synthesis of Complex Hydrazide Derivatives
4-Bromobenzoic hydrazide is utilised in the synthesis of specific hydrazide derivatives such as {2-[1-oxo-3-(4-bromophenyl)-2-propenyl]hydrazide}-4-bromobenzoic acid. This application highlights its role in constructing molecules with extended conjugated systems.
Preparation of Heterocyclic Compounds
The compound is a precursor for generating heterocyclic structures, including substituted pyrido[1,2-a]pyrimidine-2,4(3H)-diones (PPMDO). These nitrogen-containing heterocycles are of interest in medicinal chemistry research.
Building Block for Organic Synthesis
As a functionalised aromatic hydrazide, it acts as a valuable building block in multi-step organic synthesis pathways. It can be incorporated into larger molecular frameworks through various coupling and condensation reactions.
| Molecular weight | 215.05 |
|---|---|
| Linear formula | BrC6H4CONHNH2 |
| Assay | 98% |
| Application | 4-Bromobenzoic hydrazide has been used in the preparation of:• {2-[1-oxo-3-(4-bromophenyl)-2-propenyl]hydrazide}-4-bromobenzoic acid1• {2,2′-[1,4-phenylenebis(1-oxo-2-propene-3,1-diyl)]dihydrazide}-p-bromobenzoic acid1• substituted pyrido[1,2-a]pyrimidine-2,4(3H)-diones (PPMDO)2 |
| Melting point | 165-167 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromobenzoic hydrazide used for?
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4-Bromobenzoic hydrazide is primarily used as a building block in organic synthesis, for preparing complex hydrazide derivatives and heterocyclic compounds like substituted pyrido[1,2-a]pyrimidine-2,4(3H)-diones.
What is the CAS number and molecular formula for 4-Bromobenzoic hydrazide?
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The CAS number for 4-Bromobenzoic hydrazide is 5933-32-4, and its linear molecular formula is BrC<sub>6</sub>H<sub>4</sub>CONHNH<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromobenzoic hydrazide with an assay of 98%. This product is suitable for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, or EP grade.
How should 4-Bromobenzoic hydrazide be handled safely?
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According to GHS classifications, 4-Bromobenzoic hydrazide is a warning substance (GHS07) that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used during handling. Ensure adequate ventilation.
Is 4-Bromobenzoic hydrazide a controlled substance?
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The provided safety data does not indicate that 4-Bromobenzoic hydrazide is a controlled substance.
How is 4-Bromobenzoic hydrazide typically shipped and exported?
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Tech Serve Solutions, being a global supplier and exporter, packages and ships chemicals like 4-Bromobenzoic hydrazide in compliance with international shipping regulations for chemical products.
How can I request a quote or sample for 4-Bromobenzoic hydrazide?
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To request a quote or a sample of 4-Bromobenzoic hydrazide, please use the contact form on the Tech Serve Solutions website or contact our sales department directly.
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