4-Bromo-calcium Ionophore A23187
4-Bromo-calcium Ionophore A23187 (CAS: 76455-48-6, C29H36BrN3O6) is a nonfluorescent ionophore with a molecular weight of 602.52 g/mol. This compound is instrumental in scientific research for its ability to facilitate the passage of calcium ions across biological membranes. It is particularly valuable for calibrating the quantitation of cytoplasmic free Ca 2+ with fluorescent probes, aiding in the study of cellular signalling pathways.
- IUPAC
- 4-Bromo-A23187,4-Bromo-calcimycin
- Synonyms
- 4-Bromo-A231874-Bromo-calcimycin
Calcium Ion Transport Studies
Utilised as a nonfluorescent Ca 2+ ionophore, this compound aids researchers in understanding and quantifying calcium ion flux across cellular membranes. Its mechanism is crucial for studying cellular signalling pathways dependent on intracellular calcium.
Fluorescent Probe Calibration
This ionophore serves a critical role in the calibration of fluorescent probes used for measuring cytoplasmic free Ca 2+ concentrations. Accurate calibration ensures reliable data in biochemical and cell biology experiments.
Biochemical Research Reagent
As a biochemical reagent, 4-Bromo-calcium Ionophore A23187 is employed in various research settings investigating cell physiology and membrane permeability.
| Molecular weight | 602.52 |
|---|---|
| Empirical formula | C29H36BrN3O6 |
| Assay | ≥95.0% (N) |
| Solubility | ethanol: soluble20 mg/mLDMSO: soluble |
| Storage temperature | 2-8°C |
| Application | Nonfluorescent Ca2+ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca2+ with fluorescent probes. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-calcium Ionophore A23187 used for?
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4-Bromo-calcium Ionophore A23187 is used as a nonfluorescent Ca 2+ ionophore to calibrate the quantitation of cytoplasmic free Ca 2+ with fluorescent probes in scientific research settings.
What are the CAS number and molecular formula for 4-Bromo-calcium Ionophore A23187?
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The CAS number for 4-Bromo-calcium Ionophore A23187 is 76455-48-6, and its molecular formula is C29H36BrN3O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-calcium Ionophore A23187 with a purity of ≥95.0% (N). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 4-Bromo-calcium Ionophore A23187 be handled safely?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation. It may also cause respiratory irritation. Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves in a well-ventilated area. Avoid dust formation and inhalation.
How is 4-Bromo-calcium Ionophore A23187 shipped and stored?
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4-Bromo-calcium Ionophore A23187 is stored at 2-8°C. TSS exports this chemical globally and ensures appropriate packaging for safe transport.
How can I request a quote or sample for 4-Bromo-calcium Ionophore A23187?
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To request a quote or a sample of 4-Bromo-calcium Ionophore A23187, please contact our sales team through the website or by phone.
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