4-Amino-3-nitrophenylboronic acid pinacol ester
4-Amino-3-nitrophenylboronic acid pinacol ester (CAS: 833486-94-5) is an organoboron compound with the molecular formula C12H17BN2O4 and a molecular weight of 264.09 g/mol. This nitroaniline derivative is characterised by its boronate ester functional group, making it a valuable building block in organic synthesis. It is commonly employed in cross-coupling reactions and as an intermediate in the development of diverse chemical entities.
- IUPAC
- 2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Organic Synthesis Intermediate
This compound serves as a versatile intermediate in complex organic syntheses. Its structure, featuring both an amino group and a boronate ester, allows for various functionalisation strategies.
Cross-Coupling Reactions
As an arylboronate ester, it is well-suited for participation in palladium-catalysed cross-coupling reactions, such as Suzuki-Miyaura couplings, enabling the formation of carbon-carbon bonds.
Pharmaceutical Research
It can be utilised in the development of novel pharmaceutical agents and drug discovery programmes, where precise molecular architectures are required.
Material Science
The unique electronic and structural properties of this molecule may find application in the synthesis of functional materials and organic electronic components.
| Molecular weight | 264.09 |
|---|---|
| Empirical formula | C12H17BN2O4 |
| Assay | 97% |
| Melting point | 157.1-172.4 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-3-nitrophenylboronic acid pinacol ester used for?
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4-Amino-3-nitrophenylboronic acid pinacol ester is primarily used as an intermediate in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling, and in pharmaceutical research and development.
What are the CAS number and molecular formula?
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The CAS number is 833486-94-5, and the molecular formula is C12H17BN2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 97%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeia standards.
How should 4-Amino-3-nitrophenylboronic acid pinacol ester be handled safely?
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This compound is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid inhalation of dust or vapours. Refer to the safety data sheet for full handling instructions.
Is this product a controlled substance?
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Based on the provided data, there is no indication that this product is a controlled substance.
How is this chemical packed and shipped?
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This chemical is carefully packed according to international regulations for safe transport. Tech Serve Solutions is experienced in global export.
How can I request a sample or quote?
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To request a sample or obtain a quotation, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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