4,5-Dichlorothiophene-2-sulfonamide
4,5-Dichlorothiophene-2-sulfonamide (CAS: 256353-34-1) is a chemical compound with the molecular formula C4H3Cl2NO2S2 and a molecular weight of 232.11 g/mol. This halogenated heterocyclic compound serves as a valuable building block in organic synthesis. It is primarily utilised in research and development laboratories for the creation of novel molecules and complex chemical structures, particularly within the fields of medicinal chemistry and materials science.
- IUPAC
- 4,5-Dichloro-2-thiophenesulfonamide
- Synonyms
- C4H3Cl2NO2S24,5-Dichloro-2-thiophenesulfonamide

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of more complex organic molecules. Its dichlorinated thiophene structure makes it a useful precursor for introducing specific functionalities into target compounds.
Medicinal Chemistry Research
Employed in the development of new pharmaceutical agents. The thiophene core and sulfonamide group are common pharmacophores, and this compound can be a starting point for drug discovery programs.
Materials Science Applications
Potential applications in the synthesis of novel materials, such as organic semiconductors or specialised polymers, where halogenated thiophene derivatives can influence material properties.
| Molecular weight | 232.11 |
|---|---|
| Empirical formula | C4H3Cl2NO2S2 |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,5-Dichlorothiophene-2-sulfonamide used for?
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4,5-Dichlorothiophene-2-sulfonamide is primarily used as a building block in organic synthesis, particularly in medicinal chemistry research and potentially in materials science for creating new molecules and compounds.
What is the CAS number and formula for 4,5-Dichlorothiophene-2-sulfonamide?
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The CAS number is 256353-34-1 and the empirical formula is C4H3Cl2NO2S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. Specific purity and assay details are available on the product's Certificate of Analysis. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeial standards.
How should 4,5-Dichlorothiophene-2-sulfonamide be handled safely?
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This compound is a Warning: Harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation.
Is 4,5-Dichlorothiophene-2-sulfonamide a controlled substance?
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Based on the provided data, there is no indication that 4,5-Dichlorothiophene-2-sulfonamide is a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Product packaging adheres to relevant shipping regulations for safe transport. Please contact us for specific export details.
How can I request a sample or quote for 4,5-Dichlorothiophene-2-sulfonamide?
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To request a sample or a quote, please use the contact form on our website or email our sales department directly, referencing the product name and CAS number.
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