4,4′-Dimethoxytriphenylmethyl chloride
4,4′-Dimethoxytriphenylmethyl chloride (CAS: 40615-36-9) is a specialized organic compound with the molecular formula C21H19ClO2 and a molecular weight of 338.83 g/mol. It serves as a valuable reagent in chemical synthesis, particularly as a protecting group. Its utility extends to areas such as cell biology and the development of bioactive small molecules, making it a key intermediate for advanced research and development.
- IUPAC
- 4,4′-Dimethoxytrityl chloride,Chloro-4,4′-dimethoxytriphenylmethane,DMT-Cl,DMT
- Synonyms
- C21H19ClO24,4′-Dimethoxytrityl chlorideChloro-4,4′-dimethoxytriphenylmethaneDMT-ClDMT

Protecting Group in Organic Synthesis
4,4′-Dimethoxytriphenylmethyl chloride is extensively used as a protecting group for hydroxyl and amino functions in organic synthesis. Its stability and selective removal under specific conditions make it ideal for multi-step synthetic pathways.
Nucleoside and Nucleotide Chemistry
This reagent is employed in the synthesis and modification of nucleosides and nucleotides. Its application is crucial for preparing modified nucleic acid analogues for biochemical and therapeutic research.
Cell Biology Research
As a bioactive small molecule, it finds application in cell biology studies. It can be utilized to investigate cellular pathways or as a precursor for probes in biological imaging.
Synthesis of Specialty Chemicals
The compound is a precursor for various specialty chemicals and advanced intermediates. Its unique structure facilitates the synthesis of complex molecules with specific electronic or optical properties.
| Molecular weight | 338.83 |
|---|---|
| Empirical formula | C21H19ClO2 |
| Assay | ≥97.0% (HPLC) |
| Melting point | 123-125 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)rat ... Htr1a(24473), Htr2a(29595) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-Dimethoxytriphenylmethyl chloride primarily used for?
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4,4′-Dimethoxytriphenylmethyl chloride is primarily used as a protecting group in organic synthesis, particularly for hydroxyl and amino functionalities, and in the field of nucleoside and nucleotide chemistry.
What is the CAS number and formula for 4,4′-Dimethoxytriphenylmethyl chloride?
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The CAS number is 40615-36-9 and the empirical formula is C21H19ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4′-Dimethoxytriphenylmethyl chloride with a purity of ≥97.0% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling considerations for 4,4′-Dimethoxytriphenylmethyl chloride?
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According to WGK Germany, this compound has a hazard classification of 3. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling to prevent exposure.
How is 4,4′-Dimethoxytriphenylmethyl chloride typically packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures that 4,4′-Dimethoxytriphenylmethyl chloride is packed and shipped according to international regulations for chemical substances, maintaining product integrity and safety during transit.
How can I request a quote or sample for 4,4′-Dimethoxytriphenylmethyl chloride?
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To request a quote or a sample of 4,4′-Dimethoxytriphenylmethyl chloride, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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