4-[(3-(1H-Imidazol-1-yl)propyl)aminomethyl]phenylboronic acid pinacol ester
4-[(3-(1H-Imidazol-1-yl)propyl)aminomethyl]phenylboronic acid pinacol ester (CAS: 1257648-78-4) is an organoboron compound with the molecular formula C19H28BN3O2. It serves as a valuable intermediate in organic synthesis, particularly in the construction of complex molecules through cross-coupling reactions. Its structure features a boronic ester moiety and an imidazole group, making it a versatile building block for medicinal chemistry and materials science research.
- IUPAC
- N-[(3-1H-Imidazol-1-yl)propyl]-4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzylamine
- Synonyms
- N-[(3-1H-Imidazol-1-yl)propyl]-4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzylamine
![4-[(3-(1H-Imidazol-1-yl)propyl)aminomethyl]phenylboronic acid pinacol ester (C19H28BN3O2) — chemical structure, CAS 1257648-78-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1257648-78-4.png&w=3840&q=75)
Organic Synthesis Intermediate
This compound is widely used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. Its boronic ester functionality allows for efficient coupling with aryl and vinyl halides.
Medicinal Chemistry
It acts as a building block for the synthesis of novel pharmaceutical candidates. The presence of the imidazole ring and the boronic ester group provides opportunities for creating diverse molecular scaffolds with potential biological activity.
Materials Science
The compound can be utilized in the development of new functional materials. Its unique structural features may be exploited in the design of polymers, sensors, or other advanced materials.
| Empirical formula | C19H28BN3O2 |
|---|---|
| Assay | 97% |
| Melting point | 75-81 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-[(3-(1H-Imidazol-1-yl)propyl)aminomethyl]phenylboronic acid pinacol ester used for?
+
This compound is primarily used as an intermediate in organic synthesis, particularly for cross-coupling reactions like Suzuki-Miyaura coupling, and in medicinal chemistry for the development of new drug candidates.
What are the CAS number and formula for this compound?
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The CAS number is 1257648-78-4, and the molecular formula is C19H28BN3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. It is supplied for research and development purposes and is not intended for use as a USP, BP, EP, or pharmaceutical-grade substance.
What are the safety and handling precautions?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Avoid breathing dust and ensure adequate ventilation.
How is this chemical packed and shipped?
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Tech Serve Solutions ensures that chemicals are packed and exported in compliance with international shipping regulations to maintain product integrity and safety during transit.
How can I request a sample or quote?
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To request a sample or a quote for this product, please contact our sales team through the website or via email, providing the product name and CAS number.
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