4-[(2′-Chloro-5′-(trifluoromethyl)phenoxy)methyl]phenylboronic acid
4-[(2′-Chloro-5′-(trifluoromethyl)phenoxy)methyl]phenylboronic acid (CAS: 849062-05-1) is a specialised organoboron compound with the molecular formula C14H11BClF3O3 and a molecular weight of 330.49 g/mol. This aryl boronic acid derivative serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. Its structure, featuring chloro and trifluoromethyl substituents on the phenoxy ring, offers unique reactivity for constructing complex molecular architectures in research and development.
![4-[(2′-Chloro-5′-(trifluoromethyl)phenoxy)methyl]phenylboronic acid (C14H11BClF3O3) — chemical structure, CAS 849062-05-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849062-05-1.png&w=3840&q=75)
Suzuki-Miyaura Coupling Reagent
Utilised as a coupling partner in palladium-catalysed Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl and vinyl halides. This is a fundamental transformation in medicinal chemistry and materials science.
Intermediate in Pharmaceutical Synthesis
Serves as a key intermediate in the multi-step synthesis of biologically active molecules and drug candidates. Its specific structural features are leveraged to introduce complex aryl moieties into potential pharmaceuticals.
Organic Synthesis Building Block
Acts as a versatile synthon in academic and industrial research for creating novel organic compounds. Its boronic acid functionality allows for diverse chemical transformations beyond cross-coupling.
Materials Science Research
Can be employed in the synthesis of functional materials, such as organic light-emitting diodes (OLEDs) or polymers, where precise control over electronic and structural properties is required.
| Molecular weight | 330.49 |
|---|---|
| Empirical formula | C14H11BClF3O3 |
| Melting point | 165-170 °C(lit.) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Water hazard class (WGK, DE) | 3 |
|---|
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-[(2′-Chloro-5′-(trifluoromethyl)phenoxy)methyl]phenylboronic acid used for?
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This compound is primarily used as a building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the preparation of pharmaceuticals and functional materials.
What are the CAS number and formula for this chemical?
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The CAS number is 849062-05-1, and the empirical formula is C14H11BClF3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum purity of 97% (GC). We do not represent this product as USP, EP, BP or pharmacopoeia grade.
What are the safety and handling considerations?
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This product may cause long lasting harmful effects to aquatic life (H413). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid release into the environment.
Is this product suitable for direct use in pharmaceuticals or food?
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This product is intended for research and chemical synthesis purposes. It is not intended for human consumption, direct pharmaceutical use, or as a food additive.
How is this chemical packed and exported?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all relevant shipping regulations and ensuring product integrity during transit.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quotation or a sample of 4-[(2′-Chloro-5′-(trifluoromethyl)phenoxy)methyl]phenylboronic acid.
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