4-(2-Fmoc-hydrazino)benzoic acid
4-(2-Fmoc-hydrazino)benzoic acid (CAS: 214475-53-3) is a valuable organic compound with the molecular formula C22H18N2O4 and a molecular weight of 374.39 g/mol. This unnatural amino acid derivative is essential in chemical synthesis and peptide chemistry. It serves as a key building block for incorporating modified functionalities into peptide chains, facilitating research in chemical biology and the development of novel biomolecules.

Peptide Synthesis
Utilised as a specialised building block in solid-phase and solution-phase peptide synthesis to introduce unique structural features and functionalities. Its Fmoc protection allows for controlled incorporation into peptide sequences.
Chemical Biology Research
A crucial reagent for creating modified peptides or peptidomimetics, enabling the study of biological processes and protein interactions. It aids in developing probes for biological systems.
Organic Synthesis Intermediate
Serves as a versatile intermediate in the synthesis of complex organic molecules and pharmaceutical compounds, leveraging its distinct aromatic and hydrazino functionalities.
Unnatural Amino Acid Derivatives
Incorporated into research for the development and application of unnatural amino acids, expanding the scope of protein engineering and biochemical studies.
| Molecular weight | 374.39 |
|---|---|
| Empirical formula | C22H18N2O4 |
| Assay | ≥95.0% (HPLC) |
| Storage temperature | 2-8°C |
| Impurities tested | ≤1% water≤5% residual solvent |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(2-Fmoc-hydrazino)benzoic acid primarily used for?
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4-(2-Fmoc-hydrazino)benzoic acid is primarily used as a building block in peptide synthesis, chemical biology research, and general organic synthesis, particularly for creating unnatural amino acid derivatives.
What is the CAS number and molecular formula for 4-(2-Fmoc-hydrazino)benzoic acid?
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The CAS number is 214475-53-3, and the molecular formula is C22H18N2O4.
What grade and purity does Tech Serve Solutions supply for 4-(2-Fmoc-hydrazino)benzoic acid?
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Tech Serve Solutions supplies 4-(2-Fmoc-hydrazino)benzoic acid with an assay of ≥95.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 4-(2-Fmoc-hydrazino)benzoic acid be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
Is 4-(2-Fmoc-hydrazino)benzoic acid suitable for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-(2-Fmoc-hydrazino)benzoic acid, and can arrange international shipment.
How can I request a sample or quote for 4-(2-Fmoc-hydrazino)benzoic acid?
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Please contact our sales team via the website or direct email to request a sample or a detailed quotation for 4-(2-Fmoc-hydrazino)benzoic acid.
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