2-Formyl-3-thienylboronic acid
2-Formyl-3-thienylboronic acid (CAS: 4347-31-3; Formula: C5H5BO3S; MW: 155.97) is a valuable organoboron compound featuring a thiophene ring with both an aldehyde and a boronic acid group. This bifunctional molecule serves as a key building block in organic synthesis. It is particularly employed in Suzuki cross-coupling reactions and in the preparation of boronic acid esters, facilitating the construction of complex organic structures for various research and development applications.
- IUPAC
- 2-Formyl-3-thiopheneboronic acid,2-Formylthien-3-ylboronic acid,2-Formylthiophen-3-ylboronic acid
- Synonyms
- 2-Formyl-3-thiopheneboronic acid2-Formylthien-3-ylboronic acid2-Formylthiophen-3-ylboronic acid
Suzuki Cross-Coupling Reactions
2-Formyl-3-thienylboronic acid acts as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions. This allows for the formation of new carbon-carbon bonds, enabling the synthesis of diverse biaryl compounds and other complex organic molecules relevant to medicinal chemistry and materials science.
Preparation of Boronic Acid Esters
The boronic acid moiety can be readily converted into boronic acid esters. These esters are often more stable and easier to handle than the free boronic acids, making them useful intermediates for subsequent synthetic transformations or for storage.
Organic Synthesis Building Block
With its aldehyde and boronic acid functionalities on a heteroaromatic core, this compound is a versatile building block. It is used in multi-step syntheses to introduce specific structural motifs into target molecules for various research purposes.
| Molecular weight | 155.97 |
|---|---|
| Empirical formula | C5H5BO3S |
| Application | Reactant for:• Suzuki cross-coupling reactions1• Preparation of boronic acid esters2 |
| Melting point | 167-193 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Formyl-3-thienylboronic acid used for?
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2-Formyl-3-thienylboronic acid is primarily used as a reactant in Suzuki cross-coupling reactions and for the preparation of boronic acid esters. It serves as a versatile building block in organic synthesis.
What is the CAS number and formula for 2-Formyl-3-thienylboronic acid?
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The CAS number is 4347-31-3, and the empirical formula is C5H5BO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and laboratory use. The specific purity and grade are available upon request. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for 2-Formyl-3-thienylboronic acid?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Ensure good ventilation and avoid dust formation.
How is 2-Formyl-3-thienylboronic acid packed and shipped?
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This chemical is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions in compliance with all relevant regulations.
How can I request a sample or quote for 2-Formyl-3-thienylboronic acid?
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You can request a sample or a quote by contacting our sales team through the website or by calling our customer service line.
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