2-Formyl-4,5-methylenedioxyphenylboronic acid
2-Formyl-4,5-methylenedioxyphenylboronic acid (CAS: 94838-88-7) is an organic compound with the molecular formula C8H7BO5. It presents as an aryl boronic acid derivative featuring an aldehyde functional group. This versatile chemical serves as a key reactant and building block in organic synthesis, particularly for complex molecule construction via cross-coupling reactions and tandem annulations. Its utility spans the synthesis of pharmaceutical intermediates and novel organic compounds.
- Synonyms
- C8H7BO5
Suzuki-Miyaura and Negishi Cross-Coupling
This boronic acid is a valuable reagent for Suzuki-Miyaura and Negishi cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex organic synthesis pathways.
Enantioselective and Stereoselective Annulations
It participates in cationic palladium complex-catalyzed tandem annulation reactions, facilitating the enantioselective preparation of indenamines and the stereoselective synthesis of indenol derivatives.
Synthesis of Heterocycles
The compound is employed in the synthesis of oxazoline-substituted potassium organotrifluoroborates, contributing to the construction of diverse heterocyclic scaffolds.
Antitumor Agent Analog Synthesis
It serves as a precursor in the preparation of aristolactam analogs, which have been investigated for their potential antitumor activity.
| Molecular weight | 193.95 |
|---|---|
| Empirical formula | C8H7BO5 |
| Assay | ≥95% |
| Application | Reactant for:• Enantioselective preparation of indenamines by cationic palladium complex-catalyzed tandem annulation with alkynes1• Stereoselective preparation of indenol derivatives via cationic palladium complex-catalyzed diastereoselective tandem annulation2• Synthesis of oxazoline-substituted potassium organotrifluoroborates3• Preparation of aristolactam analogs as an antitumor agent4• Suzuki-Miyaura coupling reactions5• Suzuki and Negishi cross-coupling reactions6 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 2 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Formyl-4,5-methylenedioxyphenylboronic acid used for?
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2-Formyl-4,5-methylenedioxyphenylboronic acid is used as a reactant and building block in organic synthesis, including Suzuki-Miyaura coupling, Negishi coupling, and tandem annulation reactions for preparing indenamines, indenols, oxazoline-substituted potassium organotrifluoroborates, and aristolactam analogs.
What is the CAS number and molecular formula for 2-Formyl-4,5-methylenedioxyphenylboronic acid?
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The CAS number is 94838-88-7, and the molecular formula is C8H7BO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Formyl-4,5-methylenedioxyphenylboronic acid with an assay of ≥95%. We do not represent this product as USP, BP, or EP grade.
How should 2-Formyl-4,5-methylenedioxyphenylboronic acid be handled?
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This compound is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/eye protection/face protection. If in eyes, rinse cautiously with water for several minutes and seek medical advice.
Does TSS export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Formyl-4,5-methylenedioxyphenylboronic acid.
How can I request a sample or quote for 2-Formyl-4,5-methylenedioxyphenylboronic acid?
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Please contact our sales team via the website or by calling us to request a sample or a quotation for 2-Formyl-4,5-methylenedioxyphenylboronic acid.
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