[3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone
[3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone (CAS: 76855-69-1) is a chiral building block essential for asymmetric synthesis. With a molecular weight of 287.43 g/mol, this lactam derivative is vital in the creation of complex organic molecules. Its specific stereochemistry makes it a valuable intermediate in pharmaceutical research and chemical synthesis, enabling the precise construction of stereospecific compounds.
- Synonyms
- C13H25NO4Si
![[3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone (C13H25NO4Si) — chemical structure, CAS 76855-69-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F76855-69-1.png&w=3840&q=75)
Asymmetric Synthesis
This compound serves as a chiral precursor in stereoselective reactions, facilitating the synthesis of enantiomerically pure molecules. Its defined stereocentres are critical for building complex chiral structures.
Pharmaceutical Intermediates
It is employed in the development of novel drug candidates, where precise stereochemistry is crucial for biological activity and therapeutic efficacy. Its structure allows for the introduction of specific functionalities in drug synthesis pathways.
Organic Building Blocks
As a versatile organic building block, it is utilised in academic and industrial research for constructing complex molecular architectures. Researchers depend on its defined chirality for creating targeted compounds.
Lactam Chemistry
This azetidinone derivative is a key component in studies and syntheses involving lactam ring systems. Its reactivity and stereochemical integrity are well-suited for advanced organic transformations.
| Molecular weight | 287.43 |
|---|---|
| Empirical formula | C13H25NO4Si |
| Assay | 98% |
| Optical activity | [α]20/D +51°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 107-109 °C(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 36-43-51/53 |
| Safety statements (S) | 24-26-37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone used for?
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[3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in pharmaceutical research and chemical synthesis. It is valuable for constructing complex, stereospecific organic molecules.
What are the CAS number and molecular formula for this compound?
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The CAS number for [3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone is 76855-69-1. Its empirical formula is C13H25NO4Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies [3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should [3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone be handled safely?
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This compound can cause skin irritation (H317) and serious eye irritation (H319), and is toxic to aquatic life with long lasting effects (H411). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. Avoid release to the environment. Store at 2-8°C.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including [3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone. We ensure proper packaging and documentation for international shipments.
How can I request a sample or quote for this chemical?
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To request a sample or obtain a quote for [3R(1′R,4R)]-(+)-4-Acetoxy-3-[1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone, please contact our sales department via the website or by phone. Our team will assist you promptly.
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