3-Thiopheneethanol
3-Thiopheneethanol (CAS: 13781-67-4; Formula: C6H8OS; Molar Mass: 128.19 g/mol) is a valuable heterocyclic building block. This compound, also known as 2-(3-Thienyl)ethanol, is primarily utilised in chemical synthesis for the preparation of various ether and ester derivatives. Its structure, featuring a thiophene ring and a hydroxyethyl side chain, makes it a versatile intermediate in organic chemistry research and development.
- IUPAC
- 2-(3-Thienyl)ethanol,3-(2-Hydroxyethyl)thiophene
- Synonyms
- 2-(3-Thienyl)ethanol3-(2-Hydroxyethyl)thiophene
Synthesis of Ether Derivatives
3-Thiopheneethanol serves as a precursor for synthesising a range of ether derivatives, including 3-(2-(benzyloxy)ethyl)thiophene and 3-[2-((triphenylmethyl)oxy)ethyl]thiophene. These compounds can be further modified for various chemical applications.
Preparation of Ester Compounds
The compound is used in the preparation of ester derivatives such as 3-(2-acetoxyethyl)thiophene and 3-(2-(benzoyloxy)ethyl)thiophene. These esters can act as intermediates in complex organic syntheses.
Heterocyclic Intermediate
As a thiophene derivative, 3-Thiopheneethanol functions as a key building block in heterocyclic chemistry. It is employed in syntheses requiring the introduction of a 3-thienyl ethanol moiety.
| Molecular weight | 128.19 |
|---|---|
| Empirical formula | C6H8OS |
| Assay | 99% |
| Boiling point | 110-111 °C/14 mmHg(lit.) |
| Density | 1.144 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.552(lit.) |
| Application | 3-Thiopheneethanol [3-(2-hydroxyethyl)thiophene] was used in the synthesis of various ether and ester derivatives such as 3-(2-(benzyloxy)ethyl)thiophene, 3-[2-((triphenylmethyl)oxy)ethyl]thiophene, 3-[2-((trimethylsilyl)oxy)ethyl]thiophene, 3-[2-((dimethyl-tert-butylsilyl)oxy)ethyl]thiophene, 3-(2-acetoxyethyl)thiophene and 3-(2-(benzoyloxy)ethyl)thiophene1. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Thiopheneethanol used for?
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3-Thiopheneethanol is used as a building block in chemical synthesis, particularly for preparing various ether and ester derivatives.
What is the CAS number and formula for 3-Thiopheneethanol?
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The CAS number for 3-Thiopheneethanol is 13781-67-4, and its empirical formula is C6H8OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Thiopheneethanol with an assay of 99%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling 3-Thiopheneethanol?
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3-Thiopheneethanol has a flash point of 92 °C (197.6 °F) and is classified under NA 1993 / PGIII. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is 3-Thiopheneethanol packed and shipped?
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3-Thiopheneethanol is available for export globally. Packaging is designed to ensure product integrity during transit. Please contact us for specific shipping and export details.
How can I request a sample or quote for 3-Thiopheneethanol?
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To request a sample or a quotation for 3-Thiopheneethanol, please contact the Tech Serve Solutions sales team through our website or by phone.
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