3-Nitrobenzyl chloride
3-Nitrobenzyl chloride (CAS 619-23-8), with the molecular formula O2NC6H4CH2Cl and a molecular weight of 171.58, is a valuable organic building block. This compound serves as a key intermediate in chemical synthesis, particularly within the realm of nitro compounds. Its reactive benzyl chloride moiety, coupled with the electron-withdrawing nitro group, facilitates diverse organic transformations. Tech Serve Solutions supplies this chemical for research and development purposes.
- IUPAC
- α-Chloro-3-nitrotoluene
Synthesis of Heterocyclic Compounds
3-Nitrobenzyl chloride is utilised as a precursor in the synthesis of complex heterocyclic structures. Its reactivity allows for the introduction of the nitrobenzyl group into various molecular frameworks, serving as a crucial step in multi-stage organic syntheses.
Pharmaceutical Intermediate
The compound has been historically employed in the preparation of pharmaceutical intermediates. For example, it was used in the synthesis of 8-chloropurine, a significant nucleobase analogue.
Organic Synthesis Reagent
As a versatile building block, 3-Nitrobenzyl chloride finds application in a wide array of organic synthesis reactions. It enables the formation of new carbon-carbon and carbon-heteroatom bonds, contributing to the creation of novel organic molecules.
| Molecular weight | 171.58 |
|---|---|
| Linear formula | O2NC6H4CH2Cl |
| Assay | 97% |
| Boiling point | 85-87 °C/5 mmHg(lit.) |
| Application | 3-Nitrobenzyl chloride was used in the synthesis of 8-chloropurine1. |
| Melting point | 43-47 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Nitrobenzyl chloride used for?
+
3-Nitrobenzyl chloride is used as an organic building block and intermediate in chemical synthesis, including the preparation of compounds like 8-chloropurine.
What is the CAS number and chemical formula for 3-Nitrobenzyl chloride?
+
The CAS number is 619-23-8 and the chemical formula is O2NC6H4CH2Cl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Nitrobenzyl chloride with an assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for 3-Nitrobenzyl chloride?
+
3-Nitrobenzyl chloride is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, is mandatory. Handle in a well-ventilated area.
How is 3-Nitrobenzyl chloride shipped and exported?
+
3-Nitrobenzyl chloride is shipped and exported according to international regulations, designated as UN 3261, Class 8, Packing Group II.
How can I request a sample or quote for 3-Nitrobenzyl chloride?
+
To request a sample or quote for 3-Nitrobenzyl chloride, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis