3-Nitrobenzophenone
3-Nitrobenzophenone (CAS: 2243-80-3), with the molecular formula O2NC6H4COC6H5 and a molecular weight of 227.22 g/mol, is a key organic building block. This compound functions as a crucial starting reagent in the synthesis of pharmaceuticals and has applications as a plastic additive, investigated for its role in the photolytic degradation of polyolefins.

Pharmaceutical Synthesis Intermediate
3-Nitrobenzophenone serves as a vital starting material in the multi-step synthesis of ketoprofen, a widely used non-steroidal anti-inflammatory drug (NSAID).
Plastic Additive
This compound has been studied for its utility as a plastic additive. Its potential role in the photolytic degradation processes of polyethylene and polypropylene polymers in solution has been a subject of research.
Organic Synthesis Reagent
As a benzophenone derivative, 3-Nitrobenzophenone is valuable in organic synthesis for introducing specific functional groups and structural motifs in complex molecule construction.
| Molecular weight | 227.22 |
|---|---|
| Linear formula | O2NC6H4COC6H5 |
| Assay | 97% |
| Application | 3-Nitrobenzophenone was used as starting reagent in the synthesis of ketoprofen, non-steroidal anti inflammatory drug1. It was also used as plastic additive and its role in photolytic degradation of polyethylene and polypropylene in solution has been investigated2. |
| Melting point | 92-94 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Nitrobenzophenone used for?
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3-Nitrobenzophenone is primarily used as a starting reagent in the synthesis of pharmaceuticals, such as ketoprofen, and as a plastic additive.
What is the CAS number and molecular formula for 3-Nitrobenzophenone?
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The CAS number is 2243-80-3 and the molecular formula is O2NC6H4COC6H5.
What grade and purity does Tech Serve Solutions supply for 3-Nitrobenzophenone?
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Tech Serve Solutions supplies 3-Nitrobenzophenone with a minimum assay of 97%. This product is supplied for research and industrial applications and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 3-Nitrobenzophenone be handled safely?
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3-Nitrobenzophenone is classified with warning signals and carries hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. When handling, use a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation (P261) and rinse eyes thoroughly if contact occurs (P305 + P351 + P338).
Is 3-Nitrobenzophenone a controlled substance?
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The provided data does not indicate that 3-Nitrobenzophenone is a controlled substance.
How is 3-Nitrobenzophenone exported and shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Nitrobenzophenone, adhering to all international shipping and handling regulations.
How can I request a quote or sample of 3-Nitrobenzophenone?
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To request a quote or sample, please contact our sales team through the website or by phone, providing your details and the product CAS number 2243-80-3.
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