3-Methylthiophene
3-Methylthiophene (CAS 616-44-4, C5H6S) is a flammable heterocyclic organic compound with a molecular weight of 98.17 g/mol. It is a key building block in organic synthesis, particularly for creating more complex thiophene derivatives. Its characteristic properties make it valuable in research and development settings for the synthesis of novel compounds within the pharmaceutical and materials science sectors.

Chemical Synthesis Intermediate
3-Methylthiophene serves as a versatile intermediate in the synthesis of various organic molecules. It is particularly useful for introducing the 3-methylthiophene moiety into larger structures.
Heterocyclic Chemistry Research
As a thiophene derivative, this compound is integral to research exploring the properties and reactions of heterocyclic systems. Its structure allows for further functionalization and elaboration.
Materials Science Precursor
The thiophene ring is a common structural element in organic electronic materials. 3-Methylthiophene can be used as a precursor for developing novel polymers and organic semiconductors.
| Molecular weight | 98.17 |
|---|---|
| Empirical formula | C5H6S |
| Assay | ≥98.0% (GC) |
| Boiling point | 114 °C/738 mmHg(lit.) |
| Density | 1.016 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.519(lit.)n20/D 1.520 |
| Vapour pressure | 42.4 mmHg (37.7 °C) |
| Melting point | −69 °C(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H332Harmful if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 12 °C / 53.6 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20/22 |
| Safety statements (S) | 7-16-29-33-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylthiophene used for?
+
3-Methylthiophene is primarily used as a building block in organic synthesis and research, particularly in heterocyclic chemistry and for developing new materials.
What are the CAS number and formula for 3-Methylthiophene?
+
The CAS number for 3-Methylthiophene is 616-44-4, and its empirical formula is C5H6S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Methylthiophene with an assay of ≥98.0% as determined by GC. We do not represent this product as USP, BP, or EP grade.
How is 3-Methylthiophene handled and shipped?
+
3-Methylthiophene is a flammable liquid (Flash Point 12 °C) and harmful if swallowed or inhaled. It is shipped as a UN 1993, Flammable Liquid, n.o.s. (3-Methylthiophene), Hazard Class 3, Packing Group II, requiring appropriate safety precautions during handling and transport.
Can I request a sample or quote for 3-Methylthiophene?
+
Yes, you can request a sample or a quote for 3-Methylthiophene by contacting our sales department through the website.
What are the primary hazards associated with 3-Methylthiophene?
+
3-Methylthiophene is highly flammable (H225) and harmful if swallowed (H302) or inhaled (H332). Appropriate personal protective equipment, including respiratory protection, gloves, and eye protection, must be used.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis