3-Methylthiophene-2-carbonyl chloride
3-Methylthiophene-2-carbonyl chloride (CAS 61341-26-2) is a heterocyclic organic compound with the molecular formula C6H5ClOS and a molecular weight of 160.62 g/mol. This reactive acyl chloride is an important building block in organic synthesis, particularly for the introduction of the 3-methylthiophene-2-carbonyl moiety into various molecular structures. It serves as a key intermediate in the preparation of pharmaceuticals, agrochemicals, and specialised materials.

Organic Synthesis Intermediate
Utilised as a versatile reagent in organic synthesis for creating more complex molecules. It readily undergoes reactions with nucleophiles such as alcohols, amines, and thiols to form esters, amides, and thioesters, respectively.
Pharmaceutical & Agrochemical Development
Serves as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and crop protection agents. The thiophene ring system is present in numerous biologically active compounds.
Material Science
Can be employed in the synthesis of novel organic materials with specific electronic or optical properties, leveraging the characteristics of the thiophene scaffold.
| Molecular weight | 160.62 |
|---|---|
| Empirical formula | C6H5ClOS |
| Assay | 97% |
| Boiling point | 216-220 °C |
| Density | 1.314 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.586(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylthiophene-2-carbonyl chloride used for?
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3-Methylthiophene-2-carbonyl chloride (CAS 61341-26-2) is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and formula for 3-Methylthiophene-2-carbonyl chloride?
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The CAS number is 61341-26-2 and the empirical formula (Hill notation) is C6H5ClOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methylthiophene-2-carbonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Methylthiophene-2-carbonyl chloride be handled safely?
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This compound is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Handling requires appropriate personal protective equipment, including faceshields, chemical-resistant gloves, and eye protection. Ensure adequate ventilation and use a suitable respirator if exposure is likely.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Methylthiophene-2-carbonyl chloride.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quote or to arrange for a sample of 3-Methylthiophene-2-carbonyl chloride.
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