3-Methyl-2-thienylmagnesium bromide solution
3-Methyl-2-thienylmagnesium bromide solution (CAS 95184-07-9, C5H5BrMgS, MW 201.37) is a heteroaryl Grignard reagent supplied by Tech Serve Solutions as a 0.5 M solution in THF. This organometallic compound is a valuable building block in organic synthesis, particularly for introducing the 3-methyl-2-thienyl moiety into target molecules. Its reactivity makes it suitable for various coupling reactions and nucleophilic additions in the development of pharmaceuticals and fine chemicals.
Organic Synthesis Reagent
As a Grignard reagent, it is used in nucleophilic addition and substitution reactions to form new carbon-carbon bonds. It facilitates the introduction of the 3-methyl-2-thienyl group into complex organic structures.
Heteroaryl Chemistry
This compound serves as a key intermediate in the synthesis of thiophene-containing compounds. It is instrumental in constructing molecules with potential biological activity or material science applications.
Pharmaceutical Intermediate Development
The 3-methyl-2-thienyl unit is found in various pharmacologically active molecules. This reagent enables efficient routes to synthesize novel drug candidates and modify existing pharmaceutical scaffolds.
| Molecular weight | 201.37 |
|---|---|
| Empirical formula | C5H5BrMgS |
| Boiling point | 65 °C |
| Density | 0.951 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methyl-2-thienylmagnesium bromide solution used for?
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It is primarily used as a Grignard reagent in organic synthesis for introducing the 3-methyl-2-thienyl moiety into molecules, particularly in the development of pharmaceuticals and fine chemicals.
What is the CAS number and formula for 3-Methyl-2-thienylmagnesium bromide solution?
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The CAS number is 95184-07-9, and the empirical formula (Hill notation) is C5H5BrMgS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 0.5 M solution in THF. For specific lot purity, please refer to the Certificate of Analysis.
How should 3-Methyl-2-thienylmagnesium bromide solution be handled?
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This is a flammable liquid and vapour (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It may also be suspected of causing cancer (H351). It may form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment. Store refrigerated at 2-8°C.
How is this product packed, shipped, and exported?
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This chemical is classified under UN 2924, Packing Group II, for transport. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote?
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Please contact the Tech Serve Solutions sales team directly through our website or by phone to request a sample or obtain a quotation.
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