3-Methyl-2-pyridylzinc bromide solution
3-Methyl-2-pyridylzinc bromide solution (CAS: 308795-91-7) is an organozinc halide reagent with the empirical formula C6H6BrNZn and a molecular weight of 237.41 g/mol. Supplied as a 0.5 M solution in THF, it is commonly employed in organic synthesis, particularly for cross-coupling reactions and the introduction of the 3-methyl-2-pyridyl moiety into various molecular frameworks. Its reactivity makes it a valuable tool in the development of complex organic molecules.
Cross-Coupling Reactions
This organozinc reagent serves as a nucleophilic coupling partner in transition metal-catalysed reactions, such as Negishi couplings, to form new carbon-carbon bonds.
Synthesis of Heterocyclic Compounds
It is instrumental in the construction of substituted pyridine derivatives and other heteroaromatic systems, which are prevalent in pharmaceuticals and agrochemicals.
Functionalisation of Organic Molecules
The reagent enables the regioselective introduction of the 3-methyl-2-pyridyl group, facilitating the synthesis of advanced intermediates and target molecules.
| Molecular weight | 237.41 |
|---|---|
| Empirical formula | C6H6BrNZn |
| Density | 0.981 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methyl-2-pyridylzinc bromide solution used for?
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This organozinc reagent is primarily used in organic synthesis for cross-coupling reactions and the introduction of the 3-methyl-2-pyridyl group into various molecular structures.
What is the CAS number and formula for this compound?
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The CAS number is 308795-91-7 and the empirical formula is C6H6BrNZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not claim USP, BP, or EP grade for this chemical; it is intended for research and industrial applications. Please refer to the specification sheet for precise details.
How should 3-Methyl-2-pyridylzinc bromide solution be handled?
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This solution is flammable and can cause serious eye irritation and respiratory irritation. It is also suspected of causing cancer. It may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store at 2-8°C.
How is this product packed and shipped?
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This chemical is shipped as a hazardous material (UN 2924). It is packed according to regulatory requirements for flammable liquids. Tech Serve Solutions is experienced in exporting chemicals globally.
How can I request a sample or quote?
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To request a sample or a quotation, please use the contact form on our website or call our sales team, quoting the product name and CAS number.
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