3-Methyl-1-phenyl-2-phospholene 1-oxide
3-Methyl-1-phenyl-2-phospholene 1-oxide (CAS 707-61-9), with the molecular formula C11H13OP and a molecular weight of 192.19 g/mol, is a phosphorus-containing organic compound. This technical grade material is primarily utilised as a catalyst in specific organic synthesis reactions, including intramolecular aza-Wittig cyclisations and polymerisation processes. It also serves as a key reactant in the preparation of specialised compounds with potential pharmaceutical applications.
- IUPAC
- 1-Oxo-3-methyl-1-phenyl-2-phospholene,2,3-Dihydro-4-methyl-1-phenylphosphole 1-oxide,MPPO,NSC 107634
- Synonyms
- 1-Oxo-3-methyl-1-phenyl-2-phospholene2,3-Dihydro-4-methyl-1-phenylphosphole 1-oxideMPPONSC 107634
Catalyst for Aza-Wittig Cyclisation
This phospholene oxide derivative acts as an effective catalyst for intramolecular aza-Wittig cyclisation reactions, facilitating the formation of cyclic nitrogen-containing compounds in organic synthesis.
Polymerisation Catalyst
It finds application as a catalyst in various polymerisation reactions, contributing to the synthesis of polymeric materials.
Precursor for Pharmaceutical Intermediates
The compound serves as a valuable reactant for the preparation of phospha sugars and their radical bromination derivatives, which are investigated for potential anticancer activities.
| Molecular weight | 192.19 |
|---|---|
| Empirical formula | C11H13OP |
| Assay | 85% |
| Grade | technical grade |
| Boiling point | 150 °C/0.15 mmHg(lit.) |
| Refractive index | n20/D 1.5707(lit.) |
| Impurities tested | 5% dichloromethane |
| Application | Catalyst for:• Intramolecular aza-Wittig cyclization reactions1• Polymerization reactions2Reactant for preparation of:• Phospha sugars and their radical bromination derivatives as anticancer agents3 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-40 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methyl-1-phenyl-2-phospholene 1-oxide used for?
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3-Methyl-1-phenyl-2-phospholene 1-oxide is used as a catalyst for intramolecular aza-Wittig cyclisation and polymerisation reactions, and as a reactant for preparing phospha sugars and their derivatives with potential anticancer applications.
What is the CAS number and molecular formula?
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The CAS number for 3-Methyl-1-phenyl-2-phospholene 1-oxide is 707-61-9, and its molecular formula is C11H13OP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methyl-1-phenyl-2-phospholene 1-oxide in technical grade with an assay of 85%, containing approximately 5% dichloromethane. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is classified with GHS07 and GHS08 symbols, presenting hazards such as being harmful if swallowed, in contact with skin, or if inhaled, and causing skin and eye irritation, as well as potential carcinogenicity. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used. Refer to the Safety Data Sheet for comprehensive handling information.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can facilitate the export of 3-Methyl-1-phenyl-2-phospholene 1-oxide.
How can I request a quote or sample?
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To request a quote or sample of 3-Methyl-1-phenyl-2-phospholene 1-oxide, please contact our sales department through the website or by phone.
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