3-Isobutyl-1-methylxanthine
3-Isobutyl-1-methylxanthine (CAS 28822-58-4), with the molecular formula C10H14N4O2 and a molecular weight of 222.24 g/mol, is a xanthine derivative. It serves as a valuable research chemical, primarily recognised for its role as a non-specific phosphodiesterase (PDE) inhibitor. This activity makes it a useful tool in biochemical and pharmacological research for studying cellular signalling pathways and cyclic nucleotide metabolism. It is supplied by TSS with an assay of ≥99%.
- IUPAC
- 1-Methyl-3-isobutylxanthine,3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione,3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione,IBMX
- Synonyms
- IBMX1-Methyl-3-isobutylxanthine3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione
Biochemical Research
3-Isobutyl-1-methylxanthine is utilized in biochemical studies to investigate the roles of cyclic nucleotides (cAMP and cGMP) and the enzymes (phosphodiesterases) that regulate their levels. Its inhibitory action allows researchers to explore cellular responses influenced by PDE activity.
Pharmacological Tool
As a non-specific PDE inhibitor, this compound is employed in pharmacological research to understand the broader implications of PDE inhibition on various physiological processes. It helps in elucidating complex signalling cascades within biological systems.
Cell Biology Investigations
In cell biology, 3-Isobutyl-1-methylxanthine can be used to modulate intracellular cyclic nucleotide concentrations, thereby influencing cellular functions such as proliferation, differentiation, and gene expression. It is a core reagent for life science research.
| Molecular weight | 222.24 |
|---|---|
| Empirical formula | C10H14N4O2 |
| Assay | ≥99% (HPLC) |
| Solubility | DMSO: soluble1 M (with gentle warming)ethanol: soluble10 mg/mL |
| Storage temperature | −20°C |
| Melting point | 200-201 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioUltra |
|---|---|
| Gene Information | rat ... Adora1(29290), Adora2a(25369) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Isobutyl-1-methylxanthine used for?
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3-Isobutyl-1-methylxanthine is primarily used in biochemical and pharmacological research as a non-specific phosphodiesterase (PDE) inhibitor to study cellular signalling pathways and cyclic nucleotide metabolism. It is a useful tool in cell biology investigations.
What is the CAS number and formula for 3-Isobutyl-1-methylxanthine?
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The CAS number for 3-Isobutyl-1-methylxanthine is 28822-58-4, and its molecular formula is C10H14N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Isobutyl-1-methylxanthine with an assay of ≥99% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
How should 3-Isobutyl-1-methylxanthine be handled safely?
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3-Isobutyl-1-methylxanthine is classified as harmful if swallowed (H302). When handling, it is essential to wear a dust mask (type N95 US), eyeshields, face shields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is 3-Isobutyl-1-methylxanthine packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships 3-Isobutyl-1-methylxanthine to meet all regulatory requirements for global export. Storage is recommended at -20°C. Specific packaging details can be provided upon request.
How can I request a sample or quote for 3-Isobutyl-1-methylxanthine?
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To request a sample or a quote for 3-Isobutyl-1-methylxanthine, please contact our sales team through the website or by calling our office. Our representatives will be pleased to assist you.
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