3-Hydroxyazetidine hydrochloride
3-Hydroxyazetidine hydrochloride (CAS 18621-18-6) is a vital heterocyclic building block with the molecular formula C3H7NO · HCl and a molecular weight of 109.55. It is primarily employed in chemical synthesis, particularly in the pharmaceutical industry. Its defined structure and reactivity make it an important intermediate for constructing more complex molecules, notably including its use in the synthesis of fluoroquinolone antibiotics.

Pharmaceutical Synthesis Intermediate
This compound serves as a key building block in the synthesis of various pharmaceutical agents. It was notably used in a recent synthesis of a fluoroquinolone antibiotic, highlighting its importance in medicinal chemistry research and development.
Heterocyclic Chemistry
As a member of the azetidine family, 3-Hydroxyazetidine hydrochloride is valuable in heterocyclic chemistry. It allows for the introduction of the azetidine ring system into target molecules, facilitating the exploration of novel chemical entities.
Organic Synthesis Reagent
It functions as a versatile reagent in organic synthesis. Its hydrochloride salt form offers convenient handling and storage, making it a practical choice for researchers engaged in complex synthetic pathways.
| Molecular weight | 109.55 |
|---|---|
| Empirical formula | C3H7NO · HCl |
| Assay | 97% |
| Application | Building block used in a recent synthesis of a fluoroquinolone antibiotic.1 |
| Melting point | 85-90 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxyazetidine hydrochloride used for?
+
3-Hydroxyazetidine hydrochloride (CAS 18621-18-6) is used as a building block in chemical synthesis, particularly in the development of pharmaceutical compounds such as fluoroquinolone antibiotics.
What are the CAS number and chemical formula for 3-Hydroxyazetidine hydrochloride?
+
The CAS number is 18621-18-6, and the chemical formula is C3H7NO · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Hydroxyazetidine hydrochloride with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should 3-Hydroxyazetidine hydrochloride be handled?
+
Handling requires appropriate personal protective equipment, including a dust mask (N95 type US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive safety information.
Can Tech Serve Solutions export this chemical?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Hydroxyazetidine hydrochloride.
How can I request a sample or quote for 3-Hydroxyazetidine hydrochloride?
+
To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (18621-18-6).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis