3-Formylphenylboronic acid
3-Formylphenylboronic acid (CAS: 87199-16-4) is an organoboron compound with the linear formula HCOC6H4B(OH)2 and a molecular weight of 149.94 g/mol. This reagent serves as a valuable building block in organic synthesis. Its applications include participation in palladium-catalyzed coupling reactions, such as Suzuki coupling, and its use in studying the effects of boronic acids on specific chemosignaling behaviours and as probes in biological studies.
- IUPAC
- (3-Formylbenzene)boronic acid,3-(Dihydroxyboryl)benzaldehyde,3-Boronobenzaldehyde,m-formyl-benzeneboronic acid,m-Formylphenylboronic acid
- Synonyms
- 3-(Dihydroxyboryl)benzaldehyde3-Boronobenzaldehydem-formyl-benzeneboronic acidm-Formylphenylboronic acid
Suzuki Coupling Reactions
3-Formylphenylboronic acid is a key reactant in palladium-catalyzed Suzuki coupling reactions, enabling the formation of carbon-carbon bonds for complex molecule synthesis.
Chemosignaling Studies
This compound has been employed to investigate the influence of boronic acids on the fluoride-selective chemosignaling properties of merocyanine dyes.
Biological Probe Development
It has been used in the development of exciton-coupled circular dichroism (CD) probes, such as those for epigallocatechin gallate.
Enzyme Inhibition
3-Formylphenylboronic acid acts as a biological inhibitor of gamma-glutamyltranspeptidase, a key enzyme in various biological pathways.
| Molecular weight | 149.94 |
|---|---|
| Linear formula | HCOC6H4B(OH)2 |
| Application | Reagent used: • To study the effects of boronic acid on fluoride-selective chemosignaling behavior of merocyanine dye1• As exciton-coupled CD probes for epigallocatechin gallate2Biological inhibitor of γ-glutamyltranspeptidase3Reactant involved in: • Palladium-catalyzed homocoupling4• Suzuki coupling reactions5 |
| Melting point | 109-113 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Formylphenylboronic acid used for?
+
3-Formylphenylboronic acid is used as a reactant in Suzuki coupling reactions and palladium-catalyzed homocoupling, and in studies involving chemosignaling behaviour and as biological probes. It also acts as an inhibitor of gamma-glutamyltranspeptidase.
What is the CAS number and formula for 3-Formylphenylboronic acid?
+
The CAS number for 3-Formylphenylboronic acid is 87199-16-4, and its linear formula is HCOC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Formylphenylboronic acid typically as a reagent grade for research and laboratory use. Purity information is available on the Certificate of Analysis. TSS does not represent this product as USP/BP/EP or other pharmacopoeia grades.
How should 3-Formylphenylboronic acid be handled safely?
+
3-Formylphenylboronic acid is classified as Danger (GHS05) with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area.
How is 3-Formylphenylboronic acid packed and shipped?
+
3-Formylphenylboronic acid is packed and shipped according to UN 3261, Class 8, Packing Group III regulations, ensuring safe transport. TSS exports globally.
How can I request a quote or sample?
+
To request a quote or sample of 3-Formylphenylboronic acid, please contact our sales team via the website or by phone, providing your specific requirements and shipping details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis