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3-Furanboronic acid pinacol ester

CAS 248924-59-6C10H15BO3Chemical Synthesis

3-Furanboronic acid pinacol ester (CAS: 248924-59-6), with the molecular formula C10H15BO3 and a molecular weight of 194.04 g/mol, is a valuable organometallic reagent. This boronate ester derivative of furan is primarily employed in organic synthesis for the construction of complex molecules. Its specific reactivity profile makes it a useful building block in various cross-coupling reactions, particularly in the pharmaceutical and materials science sectors.

IUPAC
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)furan
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3-Furanboronic acid pinacol ester (C10H15BO3) — chemical structure, CAS 248924-59-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents
01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

3-Furanboronic acid pinacol ester serves as a key coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. This is widely used for synthesising substituted furans which are common motifs in pharmaceuticals.

Medicinal Chemistry and Drug Discovery

As a functionalized furan derivative, it is utilised in medicinal chemistry programmes for the synthesis of novel drug candidates. The furan ring is a prevalent heterocycle in biologically active compounds, and this ester allows for its precise incorporation.

Materials Science

The compound can be incorporated into the synthesis of organic electronic materials, polymers, and advanced materials where conjugated systems containing furan units are desired. These materials may possess unique optical or electronic properties.

Chemical Synthesis Building Block

Beyond specific named reactions, it functions as a versatile intermediate in multi-step organic synthesis. Its pinacol ester group offers stability and ease of handling compared to the free boronic acid.

02 /Properties
Molecular weight194.04
Empirical formulaC10H15BO3
Assay98%
Melting point62-65 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
248924-59-6
MDL number
MFCD03453669
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Furanboronic acid pinacol ester used for?

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3-Furanboronic acid pinacol ester is primarily used as a building block in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. It is also employed in medicinal chemistry for drug discovery and in materials science for developing novel compounds.

What are the CAS number and chemical formula for 3-Furanboronic acid pinacol ester?

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The CAS number is 248924-59-6 and the chemical formula is C10H15BO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-Furanboronic acid pinacol ester with an assay of 98%. This product is not represented as USP, BP, or EP grade.

How should 3-Furanboronic acid pinacol ester be handled safely?

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When handling 3-Furanboronic acid pinacol ester, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. The compound has a WGK Germany classification of 3, indicating it is hazardous.

Is 3-Furanboronic acid pinacol ester packed and shipped internationally?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Furanboronic acid pinacol ester, and can arrange for international packing and shipping.

How can I request a quote or sample for 3-Furanboronic acid pinacol ester?

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To request a quote or sample of 3-Furanboronic acid pinacol ester, please contact our sales team through the website or by phone, providing your specific requirements.

Need 3-Furanboronic acid pinacol ester in a specific grade or volume?