3′-Fluoroacetophenone
3′-Fluoroacetophenone (CAS: 455-36-7) is an organic compound with the linear formula FC₆H₄COCH₃ and a molecular weight of 138.14 g/mol. As a key aryl fluorinated building block, it serves as a versatile intermediate in organic synthesis. This fluorinated ketone is primarily utilised in the development of pharmaceuticals and agrochemicals, enabling the introduction of specific fluoroaryl moieties into complex molecular structures. Its precise chemical structure makes it valuable for research and development applications.
Pharmaceutical Intermediates
3′-Fluoroacetophenone is employed as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated aromatic ring can be incorporated into drug candidates to modulate pharmacokinetic properties, such as metabolic stability and lipophilicity.
Agrochemical Synthesis
This compound finds application in the development of novel agrochemicals. The presence of fluorine can enhance the biological activity and environmental persistence of pesticides, herbicides, and fungicides.
Organic Synthesis Reagent
As a functionalised ketone, 3′-Fluoroacetophenone acts as a versatile reagent in various organic transformations. It is useful for introducing the 3-fluorobenzoyl group into target molecules.
Materials Science
Fluorinated organic compounds are increasingly explored in materials science for applications requiring specific electronic or physical properties. 3′-Fluoroacetophenone can serve as a precursor for novel fluorinated materials.
| Molecular weight | 138.14 |
|---|---|
| Linear formula | FC6H4COCH3 |
| Assay | 99% |
| Boiling point | 81 °C/9 mmHg(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.509(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3′-Fluoroacetophenone used for?
+
3′-Fluoroacetophenone is primarily used as a building block in organic synthesis, particularly for developing pharmaceuticals, agrochemicals, and other specialty organic compounds. It is valuable for introducing fluorinated aromatic moieties into molecules.
What are the CAS number and chemical formula for 3′-Fluoroacetophenone?
+
The CAS number for 3′-Fluoroacetophenone is 455-36-7, and its linear chemical formula is FC₆H₄COCH₃.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3′-Fluoroacetophenone with an assay of 99%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 3′-Fluoroacetophenone be handled safely?
+
3′-Fluoroacetophenone is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including safety goggles, gloves, and use in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for full guidance.
How is 3′-Fluoroacetophenone packed, shipped, and exported?
+
Tech Serve Solutions packs and ships 3′-Fluoroacetophenone according to relevant dangerous goods regulations (RID/ADR: NA 1993 / PGIII). We are experienced global exporters of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for 3′-Fluoroacetophenone?
+
To request a sample or a quote for 3′-Fluoroacetophenone, please contact our sales team via the website or by phone. Please specify the quantity required and your shipping destination.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis