3-Cyanophenylboronic acid pinacol ester
3-Cyanophenylboronic acid pinacol ester (CAS: 214360-46-0) is an organoboron compound with the molecular formula C13H16BNO2 and a molecular weight of 229.08 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure, featuring both a boronate ester and a nitrile group, makes it a versatile intermediate for the preparation of complex organic molecules and pharmaceutical compounds.
- IUPAC
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
- Synonyms
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
Suzuki-Miyaura Coupling Reactions
3-Cyanophenylboronic acid pinacol ester is widely employed as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex structures.
Organic Synthesis Intermediate
This compound acts as a versatile intermediate in multi-step organic syntheses. The boronate ester moiety readily participates in various transformations, while the nitrile group can be further functionalised.
Pharmaceutical Research and Development
It is utilised in the discovery and development of new pharmaceutical agents. Its ability to introduce a cyanophenyl group is valuable for modifying molecular scaffolds in drug candidates.
Materials Science
The compound can be incorporated into the synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or functional polymers, due to its specific electronic and structural properties.
| Molecular weight | 229.08 |
|---|---|
| Empirical formula | C13H16BNO2 |
| Assay | 97% |
| Melting point | 78-82 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Cyanophenylboronic acid pinacol ester used for?
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This compound is primarily used as a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the preparation of complex organic molecules, pharmaceutical intermediates, and advanced materials.
What is the CAS number and molecular formula?
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The CAS number for 3-Cyanophenylboronic acid pinacol ester is 214360-46-0, and its molecular formula is C13H16BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Cyanophenylboronic acid pinacol ester with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 3-Cyanophenylboronic acid pinacol ester be handled?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the Safety Data Sheet for detailed handling instructions.
What are the primary hazards associated with this chemical?
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This compound is classified with a Warning signal word and carries hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation).
How is this product packed and shipped?
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3-Cyanophenylboronic acid pinacol ester is carefully packed to maintain its integrity during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a sample or quote?
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To request a sample or a quotation for 3-Cyanophenylboronic acid pinacol ester, please contact our sales team through the website or via direct inquiry.
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