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3-Chloro-4-methoxyaniline

CAS 5345-54-0ClC6H3(OCH3)NH2Chemical Synthesis

3-Chloro-4-methoxyaniline (CAS 5345-54-0) is a substituted aniline derivative with the molecular formula ClC6H3(OCH3)NH2 and a molecular weight of 157.60 g/mol. This compound functions as a valuable organic building block in chemical synthesis. It is commonly employed in the preparation of more complex molecules, particularly within the fields of pharmaceuticals and materials science, owing to its reactive amine and substituted aromatic functionalities.

IUPAC
3-Chloro-p-anisidine
Synonyms
3-Chloro-p-anisidine
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3-Chloro-4-methoxyaniline (ClC6H3(OCH3)NH2) — chemical structure, CAS 5345-54-0; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisNitrogen Compounds
01 /Applications

Pharmaceutical Intermediate

3-Chloro-4-methoxyaniline serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its structure allows for further functionalization to create complex drug molecules.

Organic Synthesis Reagent

This compound is utilised as a building block in diverse organic synthesis pathways. It is particularly useful for introducing a chloro-methoxyaniline moiety into target molecules for research and development.

Dye and Pigment Precursor

Substituted anilines are often precursors in the synthesis of dyes and pigments. 3-Chloro-4-methoxyaniline can be incorporated into chromophore structures for specialised colourant applications.

02 /Properties
Molecular weight157.60
Linear formulaClC6H3(OCH3)NH2
Assay97%
Melting point50-55 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 2233 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22
Safety statements (S)22-24/25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
5345-54-0
MDL number
MFCD00007771
PubChem substance
24853697
Beilstein registry
879162
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Chloro-4-methoxyaniline used for?

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3-Chloro-4-methoxyaniline is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and potentially dyes and pigments.

What are the CAS number and formula for 3-Chloro-4-methoxyaniline?

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The CAS number for 3-Chloro-4-methoxyaniline is 5345-54-0, and its molecular formula is ClC6H3(OCH3)NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-Chloro-4-methoxyaniline with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.

How should 3-Chloro-4-methoxyaniline be handled?

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3-Chloro-4-methoxyaniline is harmful if swallowed (H302) and requires careful handling. Use appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Avoid dust formation and breathing vapours.

Is 3-Chloro-4-methoxyaniline exported by Tech Serve Solutions?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Chloro-4-methoxyaniline.

How can I request a quote or sample for 3-Chloro-4-methoxyaniline?

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Please contact our sales team via the website or direct inquiry channels to request a quote or sample of 3-Chloro-4-methoxyaniline.

Need 3-Chloro-4-methoxyaniline in a specific grade or volume?