3-Chloro-4-methoxyaniline
3-Chloro-4-methoxyaniline (CAS 5345-54-0) is a substituted aniline derivative with the molecular formula ClC6H3(OCH3)NH2 and a molecular weight of 157.60 g/mol. This compound functions as a valuable organic building block in chemical synthesis. It is commonly employed in the preparation of more complex molecules, particularly within the fields of pharmaceuticals and materials science, owing to its reactive amine and substituted aromatic functionalities.
- IUPAC
- 3-Chloro-p-anisidine
- Synonyms
- 3-Chloro-p-anisidine

Pharmaceutical Intermediate
3-Chloro-4-methoxyaniline serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its structure allows for further functionalization to create complex drug molecules.
Organic Synthesis Reagent
This compound is utilised as a building block in diverse organic synthesis pathways. It is particularly useful for introducing a chloro-methoxyaniline moiety into target molecules for research and development.
Dye and Pigment Precursor
Substituted anilines are often precursors in the synthesis of dyes and pigments. 3-Chloro-4-methoxyaniline can be incorporated into chromophore structures for specialised colourant applications.
| Molecular weight | 157.60 |
|---|---|
| Linear formula | ClC6H3(OCH3)NH2 |
| Assay | 97% |
| Melting point | 50-55 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2233 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-methoxyaniline used for?
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3-Chloro-4-methoxyaniline is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and potentially dyes and pigments.
What are the CAS number and formula for 3-Chloro-4-methoxyaniline?
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The CAS number for 3-Chloro-4-methoxyaniline is 5345-54-0, and its molecular formula is ClC6H3(OCH3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4-methoxyaniline with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 3-Chloro-4-methoxyaniline be handled?
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3-Chloro-4-methoxyaniline is harmful if swallowed (H302) and requires careful handling. Use appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Avoid dust formation and breathing vapours.
Is 3-Chloro-4-methoxyaniline exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Chloro-4-methoxyaniline.
How can I request a quote or sample for 3-Chloro-4-methoxyaniline?
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Please contact our sales team via the website or direct inquiry channels to request a quote or sample of 3-Chloro-4-methoxyaniline.
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