(3-Bromopropyl)triphenylphosphonium bromide

CAS 3607-17-8Br(CH2)3P(C6H5)3BrChemical Synthesis

(3-Bromopropyl)triphenylphosphonium bromide (CAS: 3607-17-8) is a vital organic reagent with the molecular formula Br(CH2)3P(C6H5)3Br and a molecular weight of 466.19. This phosphonium salt is instrumental in various synthetic transformations, notably in carbon-carbon bond formation and olefination reactions. Its utility extends to the synthesis of complex organic molecules, making it a valuable component in research and development across chemical and pharmaceutical industries.

IUPAC: NSC 84074

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(3-Bromopropyl)triphenylphosphonium bromide (Br(CH2)3P(C6H5)3Br) — chemical structure, CAS 3607-17-8; Chemistry, fine chemical supplied by Tech Serve Solutions

C-C Bond FormationChemical SynthesisOlefinationSynthetic ReagentsWittig Reagents

01 /Applications

C-C Bond Formation and Olefination

This compound serves as a key reactant in Wittig reactions for the olefination of aldehydes and ketones, and in various C-C bond-forming strategies. It is employed in the synthesis of functionalized polyurethanes and in rearrangement reactions.

Synthesis of Organic Intermediates

It participates in reactions such as semipinacol rearrangement, direct arylation, and cycloisomerization of bromodienes and enynes. These transformations are crucial for building complex molecular architectures.

Polymer Chemistry

The reagent is involved in the synthesis of functionalized polyurethanes through processes including cationic ring-opening polymerization and click chemistry, enabling the development of advanced materials.

02 /Properties

Molecular weight	466.19
Linear formula	Br(CH2)3P(C6H5)3Br
Assay	98%
Application	Reactant involved in:• Synthesis of functionalized polyurethanes using cationic ring-opening polymerization and click chemistry1• Semipinacol rearrangement and direct arylation2• Olefination of benzaldehydes3• C-H activation / cycloisomerization4• Intramolecular dehydrobromination5• Cycloisomerizations of bromodienes and enynes6
Melting point	228-230 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

3607-17-8

MDL number

MFCD00011866

PubChem substance

24848072

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (3-Bromopropyl)triphenylphosphonium bromide used for?

It is used in C-C bond formation, olefination reactions (including Wittig reactions), synthesis of functionalized polyurethanes, semipinacol rearrangement, direct arylation, C-H activation/cycloisomerization, and cycloisomerizations of bromodienes and enynes.

What are the CAS number and formula for (3-Bromopropyl)triphenylphosphonium bromide?

The CAS number is 3607-17-8, and the linear formula is Br(CH2)3P(C6H5)3Br.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at a minimum assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.

How should (3-Bromopropyl)triphenylphosphonium bromide be handled?

This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.

Is (3-Bromopropyl)triphenylphosphonium bromide a controlled substance?

The provided data does not indicate that this compound is a controlled substance.

How is (3-Bromopropyl)triphenylphosphonium bromide shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details can be provided upon inquiry.