(3-Bromopropoxy)-tert-butyldimethylsilane
(3-Bromopropoxy)-tert-butyldimethylsilane (CAS: 89031-84-5), with the molecular formula Br(CH2)3OSi(CH3)2C(CH3)3 and a molecular weight of 253.25, is a valuable organic building block. This compound allows for the introduction of a protected propanol functionality into various molecules. It serves as a key intermediate in organic synthesis, particularly within the pharmaceutical sector, enabling the construction of complex molecular architectures.
Pharmaceutical Synthesis Intermediate
The tert-butyldimethylsilyl-protected propanol moiety can be efficiently incorporated into drug candidates. This functionality is crucial for the synthesis of various active pharmaceutical ingredients (APIs) where precise molecular design is required.
Organic Synthesis Reagent
This compound acts as a versatile building block in multi-step organic syntheses. It is used to introduce a three-carbon chain with a protected hydroxyl group and a terminal bromide for further functionalisation.
Material Science Applications
Its unique structure may find applications in the development of novel materials or polymers where specific functional groups are needed for cross-linking or property modification.
| Molecular weight | 253.25 |
|---|---|
| Linear formula | Br(CH2)3OSi(CH3)2C(CH3)3 |
| Assay | 97% |
| Boiling point | 182 °C(lit.) |
| Density | 1.093 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
| Storage temperature | 2-8°C |
| Contains / stabiliser | sodium carbonate as stabilizer |
| Application | The propanol functionality of this versatile reagent can be introduced to many pharmaceuticals.1,2,3,4 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 85 °C / 185 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3-Bromopropoxy)-tert-butyldimethylsilane used for?
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(3-Bromopropoxy)-tert-butyldimethylsilane is primarily used as a versatile building block in organic synthesis, particularly for introducing a protected propanol functionality into pharmaceuticals and other complex molecules.
What is the CAS number and molecular formula for (3-Bromopropoxy)-tert-butyldimethylsilane?
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The CAS number is 89031-84-5, and the molecular formula is Br(CH2)3OSi(CH3)2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (3-Bromopropoxy)-tert-butyldimethylsilane with an assay of 97%. This is a technical/research grade chemical, and TSS does not represent it as USP, BP, or EP grade.
How should (3-Bromopropoxy)-tert-butyldimethylsilane be handled?
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Handle with care as it is classified with Warning: Causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Wear appropriate personal protective equipment and ensure adequate ventilation.
How is (3-Bromopropoxy)-tert-butyldimethylsilane shipped?
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This chemical is shipped according to transport regulations (NA 1993 / PGIII). Specific shipping and handling procedures are followed to ensure safe transit and compliance.
How can I request a quote or sample?
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To request a quote or sample of (3-Bromopropoxy)-tert-butyldimethylsilane, please contact our sales team through the website or by phone, providing your specific requirements.
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