3-Bromo-5-fluoro-2-propoxyphenylboronic acid
3-Bromo-5-fluoro-2-propoxyphenylboronic acid (CAS: 868272-84-8) is an organoboron compound with the molecular formula C9H11BBrFO3 and a molecular weight of 276.90 g/mol. This compound belongs to the class of aryl boronic acids, serving as a valuable building block in organic synthesis. Its specific structure makes it useful in cross-coupling reactions and for the introduction of substituted phenyl groups in the development of complex molecules, particularly in pharmaceutical research and materials science.
Suzuki-Miyaura Cross-Coupling Reactions
This boronic acid is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds between aryl halides and organoboron compounds. It is instrumental in synthesising biaryl structures, which are common motifs in pharmaceuticals and advanced materials.
Organic Synthesis Intermediate
As a substituted phenylboronic acid, it serves as a versatile intermediate in the construction of more complex organic molecules. Its unique substitution pattern allows for regioselective functionalisation in multi-step synthetic pathways.
Pharmaceutical Research and Development
The compound is employed in medicinal chemistry for the synthesis of novel drug candidates. The presence of bromine and fluorine atoms, along with the boronic acid group, provides opportunities for diverse derivatisation and exploration of structure-activity relationships.
Materials Science
3-Bromo-5-fluoro-2-propoxyphenylboronic acid can be utilised in the development of functional materials, such as organic light-emitting diodes (OLEDs) or other electronic materials, where precise molecular architecture is crucial for desired properties.
| Molecular weight | 276.90 |
|---|---|
| Empirical formula | C9H11BBrFO3 |
| Melting point | 51-56 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-5-fluoro-2-propoxyphenylboronic acid used for?
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3-Bromo-5-fluoro-2-propoxyphenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in pharmaceutical research and materials science for the creation of complex molecules.
What are the CAS number and formula for this compound?
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The CAS number is 868272-84-8, and the empirical formula is C9H11BBrFO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific assay and purity are available upon request; it is not supplied as USP, BP, or EP grade.
How should 3-Bromo-5-fluoro-2-propoxyphenylboronic acid be handled safely?
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Based on available safety information, handle with care, using appropriate personal protective equipment including eyeshields and gloves. A respirator filter, such as type N95 (US) or type P1 (EN143), may be necessary. This compound is classified with WGK Germany 3, indicating a significant hazard.
How is 3-Bromo-5-fluoro-2-propoxyphenylboronic acid shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped and exported worldwide, adhering to all relevant regulations for chemical transport.
How can I request a sample or quote?
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To request a sample or a quotation for 3-Bromo-5-fluoro-2-propoxyphenylboronic acid, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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