3-Bromo-5-fluoro-2-isopropoxyphenylboronic acid
3-Bromo-5-fluoro-2-isopropoxyphenylboronic acid (CAS: 352534-84-0) is a substituted aryl boronic acid with the molecular formula BrC6H2(F)(OCH(CH3)2)B(OH)2 and a molecular weight of 276.90 g/mol. This organometallic reagent serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. It is frequently employed in the development of complex organic molecules, including pharmaceutical intermediates and advanced materials.
Suzuki-Miyaura Cross-Coupling Reactions
This boronic acid is a key coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds. It facilitates the synthesis of biaryl compounds and other complex aromatic structures crucial for medicinal chemistry research.
Organic Synthesis Intermediate
As a functionalised aryl boronic acid, it is used as an intermediate in multi-step syntheses. Its unique substitution pattern offers opportunities for targeted derivatisation in the creation of novel chemical entities.
Pharmaceutical Research and Development
This compound finds application in the early stages of drug discovery and development. Its structure can be incorporated into potential drug candidates, aiding in the exploration of new therapeutic agents.
| Molecular weight | 276.90 |
|---|---|
| Linear formula | BrC6H2(F)(OCH(CH3)2)B(OH)2 |
| Melting point | 63-68 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-5-fluoro-2-isopropoxyphenylboronic acid used for?
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3-Bromo-5-fluoro-2-isopropoxyphenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions and in the development of pharmaceutical intermediates and advanced materials.
What are the CAS number and chemical formula for this compound?
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The CAS number is 352534-84-0 and the linear chemical formula is BrC6H2(F)(OCH(CH3)2)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a technical/research grade. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Bromo-5-fluoro-2-isopropoxyphenylboronic acid be handled safely?
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According to GHS data, this compound is a Warning with hazards H315, H319, and H335. It is recommended to use a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure good ventilation. P261, P305 + P351 + P338 are precautionary statements.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals with rigorous attention to safety and regulatory compliance, ensuring secure transit and adherence to international shipping standards.
How can I request a sample or quote for 3-Bromo-5-fluoro-2-isopropoxyphenylboronic acid?
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To request a sample or a quote, please contact our sales department through the TSS website or by calling us directly. Our team will assist you with your specific requirements.
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