3-Bromo-2-fluorophenylboronic acid
3-Bromo-2-fluorophenylboronic acid (CAS 352535-97-8) is an organoboron compound with the molecular formula C6H5BBrFO2 and a molecular weight of 218.82 g/mol. This disubstituted aryl boronic acid is a valuable building block in organic synthesis. It is commonly employed in cross-coupling reactions, particularly Suzuki-Miyaura couplings, facilitating the formation of carbon-carbon bonds for the construction of complex organic molecules.
Suzuki-Miyaura Coupling Reagent
3-Bromo-2-fluorophenylboronic acid serves as a key coupling partner in Suzuki-Miyaura reactions. It enables the efficient synthesis of biaryl compounds and other substituted aromatic systems.
Pharmaceutical Intermediate
This compound is utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programmes, where its specific substitution pattern is beneficial for building complex drug scaffolds.
Organic Synthesis Building Block
As a versatile synthon, it is applied in the preparation of diverse organic molecules, including materials science components and agrochemical research compounds.
| Molecular weight | 218.82 |
|---|---|
| Empirical formula | C6H5BBrFO2 |
| Melting point | 225-227 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-2-fluorophenylboronic acid used for?
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3-Bromo-2-fluorophenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is also employed in the development of pharmaceuticals and other complex organic molecules.
What is the CAS number and molecular formula?
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The CAS number for 3-Bromo-2-fluorophenylboronic acid is 352535-97-8, and its empirical formula is C6H5BBrFO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromo-2-fluorophenylboronic acid. The specific grade and purity are available on the product's technical datasheet. We do not represent this product as USP/BP/EP or for food/drug/cosmetic use.
What are the safety and handling considerations for this chemical?
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Handle 3-Bromo-2-fluorophenylboronic acid with appropriate personal protective equipment, including eyeshields and gloves. A P1 (EN143) or N95 respirator is recommended. It is classified under WGK 2 in Germany.
How is this product packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packaging for all its fine chemicals, suitable for domestic and international export. Specific packaging details can be provided upon request.
How can I request a sample or a quote?
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To request a sample or a quote for 3-Bromo-2-fluorophenylboronic acid, please contact our sales team through the website or by telephone.
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