3-Bromo-1-(trimethylsilyl)-1-propyne
3-Bromo-1-(trimethylsilyl)-1-propyne (CAS 38002-45-8) is an organobromine compound with the linear formula BrCH2C≡CSi(CH3)3 and a molecular weight of 191.14 g/mol. This alkyne building block is primarily utilised in organic synthesis for the preparation of specialised molecules. Its unique structure allows for the introduction of a protected propargyl group into various chemical frameworks, facilitating complex molecular construction.
- IUPAC
- 3-(Trimethylsilyl)propargyl bromide,3-Bromo-1-(trimethylsilyl)-1-propyne
- Synonyms
- 3-(Trimethylsilyl)propargyl bromide
Preparation of Terminal Conjugated Enynes
This compound serves as a key reagent in the synthesis of terminal conjugated enynes. Its reactive propargyl bromide moiety, protected by a trimethylsilyl group, allows for controlled coupling reactions.
Synthesis of Allenic Alcohols
It is employed in the preparation of allenic alcohols, a class of compounds with diverse applications in organic chemistry and materials science. The trimethylsilyl group can be readily removed after the desired transformations.
Organic Building Block
As an organic building block, 3-Bromo-1-(trimethylsilyl)-1-propyne is valuable in constructing more complex organic molecules. It offers a versatile route to introduce a functionalised three-carbon unit.
| Molecular weight | 191.14 |
|---|---|
| Linear formula | BrCH2C≡CSi(CH3)3 |
| Assay | 98% |
| Boiling point | 44-45 °C/2 mmHg(lit.) |
| Density | 1.17 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.483(lit.) |
| Storage temperature | 2-8°C |
| Application | Employed in the preparation of terminal conjugated enynes1 and allenic alcohols.2 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-28-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-1-(trimethylsilyl)-1-propyne used for?
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3-Bromo-1-(trimethylsilyl)-1-propyne is used in organic synthesis, particularly for the preparation of terminal conjugated enynes and allenic alcohols. It acts as a valuable building block in chemical synthesis.
What is the CAS number and formula for 3-Bromo-1-(trimethylsilyl)-1-propyne?
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The CAS number is 38002-45-8 and the linear formula is BrCH2C≡CSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromo-1-(trimethylsilyl)-1-propyne with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3-Bromo-1-(trimethylsilyl)-1-propyne be handled?
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3-Bromo-1-(trimethylsilyl)-1-propyne is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment, including eyeshields and gloves, and handle in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is 3-Bromo-1-(trimethylsilyl)-1-propyne a controlled substance?
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The provided data does not indicate that 3-Bromo-1-(trimethylsilyl)-1-propyne is a controlled substance.
How is 3-Bromo-1-(trimethylsilyl)-1-propyne packed, shipped, and exported?
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3-Bromo-1-(trimethylsilyl)-1-propyne is classified under UN 3334. It is packed, shipped, and exported by TSS in compliance with all relevant transportation regulations for hazardous materials.
How can I request a sample or quote for 3-Bromo-1-(trimethylsilyl)-1-propyne?
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To request a sample or a quote for 3-Bromo-1-(trimethylsilyl)-1-propyne, please contact the TSS sales team through our website or by phone.
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