3-Bromo-1-butyne
3-Bromo-1-butyne (CAS: 18668-72-9) is an organic building block with the formula BrC(CH3)CC≡H and a molecular weight of 132.99 g/mol. This terminal alkyne features a reactive bromine atom and a triple bond, making it a versatile intermediate in organic synthesis. It is commonly employed in the construction of more complex molecules within pharmaceutical research and chemical manufacturing.
Organic Synthesis Intermediate
3-Bromo-1-butyne serves as a valuable building block for introducing alkyne and alkyl halide functionalities into target molecules. Its reactivity allows for participation in various coupling reactions and nucleophilic substitutions.
Pharmaceutical Research
This compound is utilised in the synthesis of novel pharmaceutical agents and drug candidates. Its structure can be incorporated into complex heterocyclic systems or used to create functionalised side chains.
Material Science
The unique structural features of 3-Bromo-1-butyne can be exploited in the development of specialised polymers and functional materials through controlled polymerisation or modification reactions.
| Molecular weight | 132.99 |
|---|---|
| Linear formula | BrC(CH3)CC≡H |
| Assay | ≥90% (GC) |
| Refractive index | n20/D 1.472 |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 24 °C / 75.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-36/37/38 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-1-butyne used for?
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3-Bromo-1-butyne is primarily used as a versatile intermediate in organic synthesis, particularly in pharmaceutical research and the development of new chemical entities. It facilitates the introduction of alkyne and alkyl halide functionalities into more complex molecular structures.
What is the CAS number and chemical formula for 3-Bromo-1-butyne?
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The CAS number for 3-Bromo-1-butyne is 18668-72-9, and its linear chemical formula is BrC(CH3)CC≡H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromo-1-butyne with an assay of ≥90% (GC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Bromo-1-butyne be handled safely?
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3-Bromo-1-butyne is a flammable liquid and vapour (H226), and is harmful if swallowed (H302), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Store in a well-ventilated area at 2-8°C.
Is 3-Bromo-1-butyne shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Bromo-1-butyne, and can facilitate international shipments.
How can I request a sample or quote for 3-Bromo-1-butyne?
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To request a sample or obtain a quote for 3-Bromo-1-butyne, please contact the Tech Serve Solutions sales team through our website or by phone.
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