[3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution
[3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution (CAS 480424-76-8) is an organometallic reagent, specifically a Grignard reagent, with a molecular weight of 280.44 g/mol. Supplied as a 0.25 M solution in THF, it is valuable in organic synthesis for introducing the 3-(4-morpholinylmethyl)phenyl group into various molecules. Its reactivity makes it a key intermediate in the construction of complex organic structures, particularly in the pharmaceutical and fine chemical industries.
![[3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NOC4H8MgBr) — chemical structure, CAS 480424-76-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480424-76-8.png&w=3840&q=75)
Organic Synthesis
Serves as a versatile building block in carbon-carbon bond formation reactions. Its Grignard functionality allows for nucleophilic addition to carbonyl compounds and other electrophiles, enabling the synthesis of complex molecular architectures.
Pharmaceutical Intermediates
Utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). The morpholinylmethylphenyl moiety can be incorporated into drug candidates, influencing their pharmacokinetic and pharmacodynamic properties.
Material Science
Potentially employed in the development of novel materials where the introduction of specific aryl or organometallic functionalities is required. Its reactivity can be harnessed to modify polymer backbones or create functionalised monomers.
| Molecular weight | 280.44 |
|---|---|
| Linear formula | C6H4CH2NOC4H8MgBr |
| Boiling point | 65 °C(lit.) |
| Density | 0.926 g/mL at 25 °C(lit.) |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution used for?
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[3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution is primarily used as an organometallic reagent in organic synthesis for carbon-carbon bond formation, particularly in the preparation of pharmaceutical intermediates and complex organic molecules.
What is the CAS number and formula for this compound?
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The CAS number is 480424-76-8. The linear formula is C6H4CH2NOC4H8MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies [3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution at a concentration of 0.25 M in THF. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should [3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution be handled safely?
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This compound is flammable and corrosive, causing severe skin burns and eye damage (H314). It may also cause respiratory irritation (H335) and is suspected of causing cancer (H351). Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment. It reacts violently with water.
How is this chemical packed, shipped, and exported?
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This product is shipped under UN 2924, Hazard Class 8(3), Packing Group II, reflecting its corrosive and flammable nature. Tech Serve Solutions is an experienced global exporter of fine chemicals.
How can I request a sample or a quote?
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To request a sample or a quote for [3-(4-Morpholinylmethyl)phenyl]magnesium bromide solution, please contact our sales team through the Tech Serve Solutions website or by phone.
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