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[3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution

CAS 480424-79-1C6H4CH2NC4H8MgBrChemical Synthesis

[3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution (CAS 480424-79-1) is an organometallic reagent with the linear formula C<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>NC<sub>4</sub>H<sub>8</sub>MgBr and a molecular weight of 264.44 g/mol. It is supplied as a 0.25 M solution in Tetrahydrofuran (THF). This compound serves as a valuable building block in organic synthesis, particularly for introducing the 3-(1-pyrrolidinylmethyl)phenyl moiety into target molecules through reactions characteristic of Grignard reagents.

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[3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NC4H8MgBr) — chemical structure, CAS 480424-79-1; Chemistry, fine chemical supplied by Tech Serve Solutions
ArylChemical SynthesisGrignard ReagentsOrganometallic Reagents
01 /Applications

Organometallic Synthesis

Utilized as a Grignard reagent for carbon-carbon bond formation, enabling the introduction of the 3-(1-pyrrolidinylmethyl)phenyl group in complex organic molecules.

Pharmaceutical Intermediate Synthesis

Serves as a key intermediate in the multi-step synthesis of pharmacologically active compounds, leveraging its specific functional group reactivity.

Fine Chemical Manufacturing

Employed in the production of fine chemicals where precise structural incorporation of aryl and heterocyclic elements is required.

02 /Properties
Molecular weight264.44
Linear formulaC6H4CH2NC4H8MgBr
Boiling point65 °C
Density0.922 g/mL at 25 °C
Concentration0.25 M in THF
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H314Causes severe skin burns and eye damage
  • H335May cause respiratory irritation
  • H351Suspected of causing cancer

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Flash point-17 °C / 1.4 °F
Transport (UN / ADR)UN 2924 8(3) / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xn
Risk statements (R)11-14-19-36/37/38-40
Safety statements (S)16-26-36/37
Supplemental hazardsMay form explosive peroxides., Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
480424-79-1
MDL number
MFCD03840892
PubChem substance
24880614
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is [3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution used for?

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This compound is primarily used as a Grignard reagent in organic synthesis for carbon-carbon bond formation, and as an intermediate in the synthesis of pharmaceutical and fine chemicals.

What is the CAS number and formula for [3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution?

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The CAS number is 480424-79-1 and the linear formula is C<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>NC<sub>4</sub>H<sub>8</sub>MgBr.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical as a 0.25 M solution in THF. TSS does not represent this product as USP/BP/EP or any other pharmacopoeia grade.

How should [3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution be handled and stored?

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This is a highly flammable liquid and vapour (H225), causes severe skin burns and eye damage (H314), and may cause respiratory irritation (H335). It may also be suspected of causing cancer (H351). It reacts violently with water and may form explosive peroxides. Store at 2-8°C, away from heat, sparks, and open flames, and handle under inert atmosphere.

How is [3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution packed, shipped, and exported?

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The product is packed according to safety regulations for flammable and corrosive materials and is shipped and exported as a hazardous substance (UN 2924, Class 8(3), PG II).

How can I request a sample or quote for this chemical?

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Please contact the TSS sales team via the website or by phone to request a sample or a quotation for this product.

Need [3-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution in a specific grade or volume?