[3-(1-Piperidinylmethyl)phenyl]magnesium bromide solution
[3-(1-Piperidinylmethyl)phenyl]magnesium bromide solution (CAS 480424-82-6), with the linear formula C6H4CH2NC5H10MgBr and a molecular weight of 278.47 g/mol, is an organometallic reagent. It is supplied as a 0.25 M solution in Tetrahydrofuran (THF) and serves as a valuable building block in organic synthesis, particularly for introducing functionalised aryl moieties into complex molecules. Its reactivity profile makes it suitable for various carbon-carbon bond-forming reactions.
![[3-(1-Piperidinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NC5H10MgBr) — chemical structure, CAS 480424-82-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480424-82-6.png&w=3840&q=75)
Grignard Reagent in Organic Synthesis
Utilised as a Grignard reagent for nucleophilic addition to carbonyl compounds, epoxides, and other electrophiles. This enables the formation of new carbon-carbon bonds, crucial for constructing complex organic frameworks.
Arylation Reactions
Serves as an arylating agent, introducing the [3-(1-piperidinylmethyl)phenyl] group into target molecules. This is instrumental in the synthesis of pharmaceuticals and advanced materials where specific aryl substitution patterns are required.
Precursor for Functionalised Compounds
Acts as a versatile intermediate for the preparation of diverse functionalised organic compounds. The piperidinylmethyl substituent offers a handle for further chemical modification.
| Molecular weight | 278.47 |
|---|---|
| Linear formula | C6H4CH2NC5H10MgBr |
| Boiling point | 65 °C |
| Density | 0.919 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [3-(1-Piperidinylmethyl)phenyl]magnesium bromide solution used for?
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[3-(1-Piperidinylmethyl)phenyl]magnesium bromide solution is primarily used as a Grignard reagent in organic synthesis for carbon-carbon bond formation and for introducing the [3-(1-piperidinylmethyl)phenyl] moiety into organic molecules.
What is the CAS number and formula for this compound?
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The CAS number is 480424-82-6, and the linear formula is C6H4CH2NC5H10MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 0.25 M solution in THF. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product documentation.
How should [3-(1-Piperidinylmethyl)phenyl]magnesium bromide solution be handled and stored?
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This compound is a Danger hazard (H225, H314, H335, H351), flammable (Flash Point -17 °C), and reacts violently with water. It may form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, and wear appropriate protective equipment. Store refrigerated at 2-8°C to minimise peroxide formation.
Is this chemical a controlled substance?
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The provided data does not indicate that this compound is a controlled substance. Please consult relevant local regulations for specific import/export requirements.
How are your chemicals packed and exported?
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Chemicals are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions. Specific packaging details will be provided with your order confirmation.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or contact our sales team directly with your inquiry, specifying the product name and CAS number.
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